HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Thomsen-Friedenreich antigen

Subscribe to New Research on Thomsen-Friedenreich antigen

do not confuse with T antigens, which are viral

Also Known As:

2-acetamido-2-deoxy-3-O-(beta--galactopyranosyl)-D-galactose; 2-acetamido-2-deoxy-3-O-(beta-D-galactopyranosyl)-beta-D-galactopyranose; Gal(beta-3)GalNAc; Gal(beta1-3)GalNAc; Gal-GalNAc; Galbeta(1-3)GalNAc; T antigen, mucin-type; T antigen, mucin-type carbohydrate; T mucin-type carbohydrate antigen; T-antigen, erythrocyte; T-crypt antigen; beta-D-Gal(1-3)alpha-D-GalNAc; beta-D-galactosyl(1-3)-N-acetyl-D-galactosamine; beta-galactosyl(1-3)-N-acetylgalactosamine; erythrocyte T antigen; D-Galactose, 2-(acetylamino)-2-deoxy-3-O-beta-D-galactopyranosyl-

Networked: 192 relevant articles (3 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Biological Factors: 1315
- Antigens: 114404
  - Epitopes: 7952
    - Carbohydrate Tumor-Associated Antigens: 272
      - Thomsen-Friedenreich antigen: 192
  - Neoplasm Antigens: 2058
    - Carbohydrate Tumor-Associated Antigens: 272
      - Thomsen-Friedenreich antigen: 192
- Biological Markers: 56388
  - Biological Tumor Markers: 4681
    - Carbohydrate Tumor-Associated Antigens: 272
      - Thomsen-Friedenreich antigen: 192

Experts

1.	Sakuma, Shinji: 7 articles (03/2015 - 10/2008)
2.	Kurtenkov, Oleg: 6 articles (01/2015 - 08/2002)
3.	Klaamas, Kersti: 6 articles (01/2015 - 08/2002)
4.	Petri, William A: 6 articles (01/2011 - 01/2004)
5.	Glinskii, Olga V: 5 articles (03/2014 - 07/2003)
6.	Glinsky, Vladislav V: 5 articles (03/2014 - 07/2003)
7.	Rittenhouse-Olson, Kate: 5 articles (03/2014 - 08/2002)
8.	Kataoka, Makoto: 5 articles (05/2013 - 10/2008)
9.	Tachikawa, Hiroyuki: 5 articles (05/2013 - 10/2008)
10.	Karsten, Uwe: 5 articles (05/2013 - 01/2007)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2001 - "We conclude that Gal-GalNAc is an early and intermediate biomarker, suitable not only for the detection of malignancy in its inception, but also for monitoring of people at high risk for cancer, and the efficacy of the cancer therapy as well as secondary prevention by this technology." 08/01/1998 - "To study the immunohistochemical expression of the Thomsen-Friedenreich antigen (T) and its precursor, Tn, in the skin in various cancers. " 07/01/2015 - "One example of such changes is demasking of the otherwise hidden core-1 structure, also known as Thomsen-Friedenreich antigen, which is a highly tumor-specific glycotope and potentially a cancer stem cell marker. " 09/10/2014 - "A tandem enzymatic approach for detecting and imaging tumor-associated Thomsen-Friedenreich antigen disaccharide." 10/01/2013 - "CD176 (Thomsen-Friedenreich antigen) is a tumor-associated carbohydrate structure. "
2.	Amebiasis (Amoebiasis) 01/17/2011 - "Amebiasis in the murine model can be prevented by vaccination with the Gal/GalNAc lectin through a T cell-dependent mechanism. " 03/01/2007 - "Stable expression of Gal/GalNAc lectin of Entamoeba histolytica in transgenic chloroplasts and immunogenicity in mice towards vaccine development for amoebiasis." 03/01/2004 - "Evaluation of recombinant fragments of Entamoeba histolytica Gal/GalNAc lectin intermediate subunit for serodiagnosis of amebiasis." 01/01/2004 - "The Gal/GalNAc lectin (Gal-lectin) of Entamoeba histolytica is a surface molecule involved in parasite adherence to host cells and is the most promising subunit vaccine candidate against amoebiasis. " 10/01/1987 - "The humoral response to the Gal/GalNAc-binding lectin of the parasite may contribute to the development of protective immunity against invasive amebiasis."
3.	Colonic Neoplasms (Colon Cancer) 07/01/2001 - "Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44." 05/01/2001 - "Increasing the intra-Golgi pH of cultured LS174T goblet-differentiated cells mimics the decreased mucin sulfation and increased Thomsen-Friedenreich antigen (Gal beta1-3GalNac alpha-) expression seen in colon cancer." 02/01/2001 - "Opposite effects on human colon cancer cell proliferation of two dietary Thomsen-Friedenreich antigen-binding lectins." 07/01/1996 - "The disaccharide tumor marker Gal-GalNAc visualized by galactose oxidase-Schiff sequence is commonly present in cancer cells and in rectal mucous of patients with colon cancer. " 11/01/1995 - "The tumor mucin marker Gal-GalNAc, expressed by precancer and cancer of colon, but not by the normal cells showed a time-dependent biphasic change by InsP6; an increased expression after 1 day of treatment followed by suppression after 2 days suggest progression of mucin synthesis and differentiation of cancer cells with reversion to normal phenotype. "
4.	Urinary Bladder Neoplasms (Bladder Cancer) 02/01/1988 - "[Study of the Thomsen-Friedenreich antigen in bladder tumors]." 04/01/1987 - "[The study of Thomsen-Friedenreich antigen and prognosis of the patients with bladder tumor]." 03/01/1985 - "[The study on Thomsen-Friedenreich antigen in bladder tumor]." 02/01/2014 - "The Thomsen-Friedenreich antigen (TF-Ag) is a disaccharide hidden on normal cells, but selectively exposed on the surface of breast, colon, prostate and bladder cancer cells. " 02/01/1988 - "Thomsen-Friedenreich antigen in bladder cancer tissues detected by monoclonal antibody."
5.	Carcinoma (Carcinomatosis) 03/01/2015 - "Expression of MUC1 and CD176 (Thomsen-Friedenreich antigen) in papillary thyroid carcinomas." 01/01/2007 - "The Thomsen-Friedenreich antigen (TF, CD176) is a specific oncofetal carbohydrate epitope (Gal beta1-3GalNAc alpha-O-Ser/Thr) expressed on the surface of various carcinomas. " 11/01/2006 - "Thomsen-Friedenreich antigen (TF-Ag) is expressed in many carcinomas, including those of the breast, colon, bladder, and prostate. " 01/01/2004 - "The Thomsen-Friedenreich antigen, a carcinoma-associated disaccharide involved in carcinoma cell homotypic aggregation and increased metastatic potential, has clinical value as a prognostic indicator and a marker of metastasized cells. " 02/07/2003 - "The importance of Thomsen-Friedenreich antigen (T antigen)-galectin-3 interactions in adhesion of human breast carcinoma cells to the endothelium under conditions of flow was studied. "

Related Drugs and Biologics

1.	Antigens
2.	Mucins
3.	Immune Sera (Antisera)
4.	Isoantigens (Alloantigen)
5.	Tumor Viral Antigens (Large T Antigen)
6.	Surface Antigens (Surface Antigen)
7.	Antibodies
8.	Galactose (Galactopyranose)
9.	Galectin 3 (LGALS3)
10.	Monoclonal Antibodies

Related Therapies and Procedures

1.	Chemoprevention
2.	Drug Therapy (Chemotherapy)
3.	Nanospheres
4.	Immunotherapy
5.	Cystectomy