HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

pentachloroethane

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Chlorinated Hydrocarbons: 240
      - pentachloroethane: 3
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Ethane: 225
        pentachloroethane: 3

Related Diseases

1.	Carcinogenesis 04/01/1983 - "Carcinogenesis Studies of Pentachloroethane (CAS No. 76-01-7) in F344/N Rats and B6C3F1 Mice (Gavage Study)." 04/01/1983 - "A carcinogenesis bioassay of technical grade pentachloroethane (95.5% pure, with 4.2% hexachloroethane) was conducted by administering the test chemical in corn oil by gavage to groups of 50 male and 50 female F344/ N rats at doses of 75 or 150 mg/ kg body weight and to groups of 50 male and 50 female B6C3F1 mice at doses of 250 or 500 mg/ kg. (Pentachloroethane is a solvent that was used primarily as an intermediate in the manufacture of tetrachloroethylene.) Doses were administered for 103 weeks for rats and 41-103 weeks for mice. "
2.	Hepatocellular Carcinoma (Hepatoma) 04/01/1983 - "Technical grade pentachloroethane was carcinogenic for B6C3F1 mice, causing hepatocellular carcinomas in males and females, and adenomas in females. " 04/01/1987 - "Trichloroethylene (TCE), perchloroethylene (PER), and pentachloroethane (PENT) are widely used industrial chemicals that cause an increased incidence of hepatocellular carcinoma in mice and a very low incidence of renal tubular adenocarcinoma in rats. "
3.	Polyploidy 08/12/1996 - "Six of nine chemicals induced chromosomal aberrations; bromodichloromethane, chlorendic acid and isophorone induced structural aberrations, and chlorodibromomethane, pentachloroethane and 1,1,1,2-tetrachloroethane induced numerical aberrations (polyploidy). "
4.	Neoplasms (Cancer) 04/01/1983 - "The National Toxicology Program considers that these rare tubular-cell tumors of the kidney in male rats indicate a target organ and may have been associated with the administration of pentachloroethane. " 04/01/1983 - "Pentachloroethane administration did not cause any increased incidences of tumors in either male or female rats. "
5.	Chromosome Aberrations (Chromosome Abnormalities) 08/12/1996 - "Six of nine chemicals induced chromosomal aberrations; bromodichloromethane, chlorendic acid and isophorone induced structural aberrations, and chlorodibromomethane, pentachloroethane and 1,1,1,2-tetrachloroethane induced numerical aberrations (polyploidy). "

Related Drugs and Biologics

1.	Tetrachloroethylene (Tetrachloroethene)
2.	Trichloroethylene (Trichloroethene)
3.	Solvents
4.	Corn Oil (Oil, Corn)
5.	chlorendic acid
6.	chlorodibromomethane
7.	1,1,1,2-tetrachloroethane
8.	bromodichloromethane
9.	hexachloroethane
10.	isophorone