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pentaacetylgitoxin
structure; RN given refers to (3beta,5beta,16beta)-isomer
Also Known As:
Pentagit; pengitoxin; pentaacetylgitoxin, (3beta,5beta,12beta)-isomer; pentaacetylgitoxin, (3beta,5beta,16alpha)-isomer
Networked:
5
relevant articles (
2
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Cardanolides
Cardiac Glycosides: 1002
Cardenolides: 137
Digoxin: 4157
Acetyldigoxins: 18
pentaacetylgitoxin: 5
Digitalis Glycosides: 147
Digoxin: 4157
Acetyldigoxins: 18
pentaacetylgitoxin: 5
Carbohydrates: 22023
Glycosides: 2119
Cardiac Glycosides: 1002
Digitalis Glycosides: 147
Digoxin: 4157
Acetyldigoxins: 18
pentaacetylgitoxin: 5
Related Diseases
1.
Heart Failure
01/01/1988 - "
Pharmacokinetics of pengitoxin and its therapeutic efficacy in congestive heart failure.
"
01/01/1988 - "
In a therapeutic study, 120 inpatients suffering from congestive heart failure were treated with a daily maintenance dose of 0.3 mg pengitoxin (penta-acetyl-gitoxin) over several weeks or months.
"
07/01/1982 - "
Color discrimination ability of 53 patients with congestive heart failure and 32 healthy volunteers treated with digoxin, digitoxin, or pengitoxin was determined with the Farnworth's Munsell 100 hue test.
"
10/01/1988 - "
Color discrimination ability of 100 in-patients suffering from congestive heart failure and treated with digitoxin (D), pengitoxin (P), or digoxin (Dg) was determined with the Farnsworth-Munsell 100 Hue test (FM 100) and compared with the color discrimination of 72 in-patients who were not treated with digitalis glycosides (control group C).
"
2.
Sexually Transmitted Diseases (Sexually Transmitted Disease)
01/01/1987 - "
The efficacy of pengitoxin estimated by shortening of STI justifies the administration of daily maintenance doses between 0.30 and 0.45 mg.
"
01/01/1987 - "
The shortening of STI observed after therapeutic and subtoxic doses of pengitoxin was in accordance with that after intake of digitoxin and digoxin in corresponding doses.
"
3.
Neoplasm Metastasis (Metastasis)
07/01/1987 - "
In ten patients suffering from moderate to severe disturbances of liver function (hepatic cirrhosis, carcinomatous metastases of the liver) the elimination of 16-acetyl-gitoxin from plasma was measured after a single oral dose of 1.2 mg pengitoxin.
"
4.
Liver Cirrhosis (Hepatic Cirrhosis)
07/01/1987 - "
In ten patients suffering from moderate to severe disturbances of liver function (hepatic cirrhosis, carcinomatous metastases of the liver) the elimination of 16-acetyl-gitoxin from plasma was measured after a single oral dose of 1.2 mg pengitoxin.
"
Related Drugs and Biologics
1.
PENTA
2.
gitoxin
3.
Digoxin (Digitek)
4.
Digitoxin
5.
Digitalis Glycosides
6.
FM 100 (FM100)
7.
16-acetylgitoxin