modeccin

from Modecca Digitata Harv, passifloracea growing in austral Africa; fruits & roots are very poisonous to man; also isolated from Adenia digitata

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

1.	Ascites 08/15/1982 - "Effect of ricin, of its subunits and of modeccin on cAMP level in Yoshida ascites cells." 08/15/1978 - "3. Modeccin inhibits protein synthesis in vitro in a lysate of rabbit reticulocytes and in Ehrlich ascites cells; the effect on cells is decreased in the presence of lactose. "
2.	Vesicular Stomatitis 10/01/1984 - "DTG 1-5-4 exhibited increased resistance to modeccin, Pseudomonas toxin, diphtheria toxin, Sindbis virus, and vesicular stomatitis virus, as well as decreased uptake via the mannose 6-phosphate receptor. "
3.	Poisoning 05/24/1979 - "1. Rat liver microsomes isolated at 6 and 12 h of poisoning with 3 x LD50 (0.3 microgram/100 g body wt.) of modeccin, the toxin of Adenia digitata, have a decreased capacity of protein synthesis in vitro. "
4.	Diphtheria 12/01/1986 - "Activities affected at 41 degrees C include uptake via the D-mannose 6-phosphate receptor, accumulation of Fe from diferric transferrin, uptake of alpha 2-macroglobulin, compartmentalization of newly synthesized acid hydrolases, resistance to ricin, and sensitivity to diphtheria and Pseudomonas toxins and modeccin. "

1.	Ricin
2.	Proteins (Proteins, Gene)
3.	Mannose (D-Mannose)
4.	Pregnancy-Associated alpha 2-Macroglobulins (alpha 2 Macroglobulin)
5.	Lactose
6.	Hydrolases
7.	Diphtheria Toxin
8.	Acids
9.	diferric transferrin