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hexocyclium (hexocyclium methylsulfate)

RN given refers to parent cpd; structure

Also Known As:

hexocyclium methylsulfate; hexociclium; 4-(2-cyclohexyl-2-hydroxy-2-phenethyl)-1,1- dimethylpiperazinium

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Drug Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - hexocyclium: 6

Related Diseases

1.	Peptic Ulcer (Peptic Ulcers) 05/01/1958 - "Hexocyclium (tral) in the treatment of peptic ulcer and its effect on human gastric secretion." 01/01/1958 - "Hexocyclium methosulfate, a new anticholinergic drug in conventional and long-acting forms: its effects on gastric secretion; the effects of hexocyclium (a) on the pH of gastric secretion as studied by 48-hour gastric analysis, (b) on volume and acidity of nocturnal secretion, and (c) in the management of peptic ulcer."
2.	Duodenal Ulcer (Curling's Ulcer) 09/01/1963 - "EFFECT OF HEXOCYCLIUM METHYLSULFATE ON INTRAGASTRIC PH IN PATIENTS WITH DUODENAL ULCER." 01/01/1958 - "Hexocyclium methosulfate in active duodenal ulcer; evaluation of a new anticholinergic drug in conventional and long-acting forms, especially its effect on gastric pH as studied in 48-hour analysis."
3.	Ulcer 01/14/1966 - "[Experiences in the treatment of hyperacid ulcer patients with Hexocyclium]."
4.	Neuroblastoma 06/01/1994 - "1. We have compared the binding properties of several hexocyclium and sila-hexocyclium derivatives to muscarinic M1 receptors (in rat brain, human neuroblastoma (NB-OK 1) cells and calf superior cervical ganglia), rat heart M2 receptors, rat pancreas M3 receptors and M4 receptors in rat striatum, with their functional antimuscarinic properties in rabbit vas deferens (M1/M4-like), guinea-pig atria (M2), and guinea-pig ileum (M3) muscarinic receptors. "

Related Drugs and Biologics

1.	Cholinergic Antagonists (Anticholinergics)
2.	Muscarinic M1 Receptor
3.	Muscarinic M3 Receptor
4.	Muscarinic Antagonists
5.	silahexocyclium