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pumitepa

structure; RN given refers to unlabeled cpd

Also Known As:

2-dimethylamino-6-diethyleneiminophosphamido-7-methylpurine; fopurin; phopurinum; pumitepa, 32P-labeled

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azirines
    - Aziridines: 14
      - pumitepa: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - pumitepa: 3

Related Diseases

1.

Chromosome Aberrations (Chromosome Abnormalities)

11/05/1990 - "Sister chromatid exchanges (SCEs) and structural chromosome aberrations (CAs) induced by cytostatic drug phopurinum in vivo and in vitro were studied in human lymphocytes. "
05/01/1989 - "[Effect of natural human leukocyte interferon on cell cycle kinetics, the frequency of sister chromatid exchanges and chromosome aberrations in fopurin-treated human lymphocytes]."
09/15/1989 - "Induction of sister chromatid exchanges (SCEs) and chromosome aberrations (CAs) by two antineoplastic drugs--phopurinum (2-dimethylamino-6-diethyleneiminophosphamido-7-methylpurine) and recombinant human interferon alpha 2 (rHuIFN-alpha 2) was studied in human lymphocytes in vitro. "
05/01/1989 - "Interferon pretreatment decreased the levels of the SCE induced by antineoplastic alkylating drug fopurin (2-dimethylamino-6-diethylene iminophosphamido-7-methylpurine; treatment conditions: the 20-24 hour incubation time, 25 and 50 microM), but no statistically significant changes were noticed in AGTs, in the number of aberrant metaphases, and in the total number of induced chromosome aberrations (CA). "

Related Drugs and Biologics

1.	Antineoplastic Agents (Antineoplastics)
2.	Cytostatic Agents
3.	Interferon-alpha (Interferon Alfa)
4.	Interferons
5.	Interferon alpha-2 (Roferon-A)