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dimethyl-4-toluidine

Also Known As:

N,N-dimethyl-p-toluidine; dimethyl-p-toluidine; dimethyl-para-toluidine

Networked: 9 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - Toluidines: 2
      - dimethyl-4-toluidine: 9
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Toluene: 931
        Toluidines: 2
        dimethyl-4-toluidine: 9

Experts

1.	Chang, Yu-Chao: 2 articles (01/2008 - 07/2007)
2.	Huang, Fu-Mei: 2 articles (01/2008 - 07/2007)
3.	Li, Yi-Ching: 2 articles (01/2008 - 07/2007)
4.	Lin, Ruey-Hseng: 2 articles (01/2008 - 07/2007)
5.	Brix, Amy: 1 article (01/2016)
6.	Dunnick, June K: 1 article (01/2016)
7.	Flake, Gordon: 1 article (01/2016)
8.	Foley, Julie: 1 article (01/2016)
9.	Gerrish, Kevin: 1 article (01/2016)
10.	Merrick, B Alex: 1 article (01/2016)

Related Diseases

1.	Chromosome Aberrations (Chromosome Abnormalities) 01/01/2008 - "In this study, 9F in the presence or absence of reducing agent N,N-dimethyl-p-toluidine (DMT) with or without VL irradiation was analyzed for the induction of chromosomal aberrations indicated by micronuclei (MN) induced in CHO cells. " 07/01/2007 - "In this study, CQ in the presence of reducing agent N,N-dimethyl-p-toluidine (DMT) with or without VL irradiation was analyzed for the induction of chromosomal aberrations indicated by micronuclei (MN) induced in CHO cells. "
2.	Carcinogenesis 09/01/2012 - "Toxicology and carcinogenesis studies of N,N-dimethyl-p-toluidine (CAS No. 99-97-8) in F344/N rats and B6C3F1/N mice (gavage studies)." 09/01/2012 - "N,N-dimethyl-p-toluidine was nominated for toxicology and carcinogenesis studies by the National Cancer Institute based on the potential for human exposure through its use in dental materials and bone cements and the lack of toxicity and carcinogenicity data. "
3.	Neoplasms (Cancer) 01/01/2016 - "N, N-dimethyl-p-toluidine (DMPT; Cas No. 99-97-8), an accelerant for methyl methacrylate monomers in medical devices, is a nasal cavity carcinogen according to a 2-yr cancer study of male and female F344/N rats, with the nasal tumors arising from the transitional cell epithelium. "
4.	Body Weight (Weight, Body) 09/01/2012 - "2-YEAR STUDY IN RATS: Groups of 50 male and 50 female rats were administered 0, 6, 20, or 60 mg N,N-dimethyl-p-toluidine/kg body weight in corn oil by gavage, 5 days per week for 104 or 105 weeks. " 09/01/2012 - "3-MONTH STUDY IN MICE: Groups of 10 male and 10 female mice were administered 0, 15, 30, 60, 125, or 250 mg N,N-dimethyl-p-toluidine/kg body weight in corn oil by gavage, 5 days per week for 14 weeks. " 09/01/2012 - "3-MONTH STUDY IN RATS: Groups of 10 male and 10 female rats were administered 0, 62.5, 125, 250, 500, or 1,000 mg N,N-dimethyl-p-toluidine/kg body weight in corn oil by gavage, 5 days per week for 14 weeks. "
5.	Methemoglobinemia 10/01/1988 - "An acute cyanotic episode due to methemoglobinemia occurred in a 16-month old girl following the ingestion of N,N-dimethyl-p-toluidine, a commercially available component used in the production of artificial fingernails. " 10/01/1988 - "Methemoglobinemia due to ingestion of N,N-dimethyl-p-toluidine, a component used in the fabrication of artificial fingernails." 12/01/2022 - "One example of an uncommon cause of acquired methemoglobinemia is the ingestion of nail polish remover, which can contain methemoglobin generators such as nitroethane, N,N-dimethyl-p-toluidine, and isobutyl nitrite. "

Related Drugs and Biologics

1.	Reducing Agents
2.	Dental Materials
3.	Methacrylates
4.	Corn Oil (Oil, Corn)
5.	Carcinogens
6.	Bone Cements (Bone Glue)
7.	dimethylpropiothetin (dimethylsulfoniopropionate)
8.	Methemoglobin
9.	Acetone
10.	acetonitrile