1,2-benzisothiazoline-3-one (benzisothiazolinone)

10/01/1998 - "The benzisothiazolone 3, the cyclic derivative of 2, was selected for clinical trials as an agent for AIDS therapy. "

11/28/2023 - "Occupational allergic contact dermatitis due to benzisothiazolinone in an emulsifying oil."
11/01/2020 - "Occupational allergic contact dermatitis due to undeclared benzisothiazolinone in an emulsifying oil."
02/01/2020 - "The high concentrations of these substances and other isothiazolinones such as benzisothiazolinone (BIT) and octylisothiazolinone (OIT) contained in cleaning products may cause allergic contact dermatitis in sensitized patients. "
09/01/2009 - "Allergic contact dermatitis to 1,2-benzisothiazolin-3-one in the water softener manufacturing industry."
04/01/2003 - "Occupational allergic contact dermatitis from 1,2-benzisothiazolin-3-one without cross-sensitization to other isothiazolinones."

12/01/2021 - "The prevalence of contact allergy to benzisothiazolinone (BIT) has increased steadily increased in 2014 from 0.26% (confidence interval [CI] 0.03-0.93) to 3.42% (CI 2.43-4.66) in 2019. "
12/01/2021 - "Trends in preservative allergy: Benzisothiazolinone emerges from the pack."
11/01/2016 - "Contact allergy to 1,2-benzisothiazolin-3-one."
11/01/2013 - "To investigate the prevalence of contact allergy to MI, MCI/MI and benzisothiazolinone (BIT) among patch tested patients at Gentofte Hospital, as well as the use of MI in cosmetic products. "
09/01/1992 - "Occupational contact allergy to 1,2-benzisothiazolin-3-one in the manufacture of air fresheners."

03/01/2006 - "Patch tests with readings at 48 and 96 hours were performed with the North American Contact Dermatitis Group standard series and benzisothiazolinone. "
08/01/2005 - "Occupational contact dermatitis to 1,2-benzisothiazolin-3-one and 5-chloro-2-methylisothiazolin-3-one/2-methylisothiazolin-3-one in paint manufacturers."
04/01/1980 - "Contact dermatitis due to benzisothiazolone in a works analytical team."
01/01/2004 - "Dermal exposure to ready-to-use glyphosate formulations can cause irritation and photo-contact dermatitis has been reported occasionally; these effects are probably due to the preservative Proxel (benzisothiazolin-3-one). "
05/01/1981 - "Contact dermatitis from benzisothiazolone in cutting oils."

11/01/2012 - "Systemic allergic dermatitis following airborne exposure to 1,2-benzisothiazolin-3-one."
10/01/2006 - "Small amounts of benzisothiazolinone in the gloves may sensitize those who already have hand dermatitis. "
04/01/1999 - "Occupational hand dermatitis due to 1,2-benzisothiazolin-3-one in the water-softener manufacturing industry."
10/01/2006 - "We recommend that all patients with hand dermatitis while using PVC gloves should be patch tested with benzisothiazolinone."
10/01/2006 - "We found a total of 8 patients who are allergic to benzisothiazolinone and who had had exacerbations of their hand dermatitis while using PVC gloves. "