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zymosterol

a 4,14-desmethyl intermediate between LANOSTEROL and CHOLESTEROL

Also Known As:

5 alpha-cholesta-8,24-dien-3 beta-ol

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Cholestanes
      - Sterols: 2245
        Cholesterol: 67133
        zymosterol: 6
      - Cholestenes
        Cholesterol: 67133
        zymosterol: 6
Lipids: 114793
- Membrane Lipids: 1591
  - Sterols: 2245
    - Cholesterol: 67133
      - zymosterol: 6

Experts

1.	Aigrot, Marie-Stephane: 1 article (11/2021)
2.	Bachelin, Corinne: 1 article (11/2021)
3.	Lamari, Foudil: 1 article (11/2021)
4.	Lubetzki, Catherine: 1 article (11/2021)
5.	Martin, Elodie: 1 article (11/2021)
6.	Nait Oumesmar, Brahim: 1 article (11/2021)
7.	Stankoff, Bruno: 1 article (11/2021)
8.	Zalc, Bernard: 1 article (11/2021)
9.	Di Lucente, Jacopo: 1 article (11/2020)
10.	Hu, Ying: 1 article (11/2020)

Related Diseases

1.	Glucose Intolerance 11/06/2020 - "Among the top 10 most affected metabolites, FPC-fed mice had marked increase of zymosterol, a cholesterol biosynthesis metabolite, and reduced 2,8-dihydroxyquinoline, which has known benefits in reducing glucose intolerance; these changes were reversible by inulin supplementation. "
2.	Multiple Sclerosis 11/01/2021 - "TF enhances zymosterol accumulation in oligodendrocytes and CNS myelin repair, a beneficial off-target effect that should be investigated in patients with multiple sclerosis."
3.	Melanoma (Melanoma, Malignant) 01/05/2016 - "We discovered six novel associations between activation of metabolic molecular pathways and progression of melanoma: for allopregnanolone biosynthesis, L-carnitine biosynthesis, zymosterol biosynthesis (inhibited in melanoma), fructose 2, 6-bisphosphate synthesis and dephosphorylation, resolvin D biosynthesis (activated in melanoma), D-myo-inositol hexakisphosphate biosynthesis (activated in primary, inhibited in metastatic melanoma). "
4.	Autolysis 07/01/1999 - "Yeast autolysis induced a decrease of esterified sterol content, especially first intermediates in the sequence of the ergosterol biosynthesis, as zymosterol. "
5.	Acute-Phase Reaction 10/17/2016 - "Canonical pathway analysis demonstrated changes in acute phase response signaling, aryl hydrocarbon receptor signaling, NRF-2 mediated oxidative stress, and zymosterol biosynthesis in the 60 and 100 μg·kg-1 HD dose group. "

Related Drugs and Biologics

1.	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)
2.	Sterols
3.	Pregnanolone (Allopregnanolone)
4.	Phytic Acid (Inositol Hexaphosphate)
5.	Inulin
6.	Fructose
7.	Ergosterol (Lumisterol)
8.	Desmosterol
9.	Cholesterol
10.	Carnitine (L-Carnitine)