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perilla ketone
potent lung toxin from Perilla frutescens; structure
Networked:
10
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
Monoterpenes: 522
perilla ketone: 10
Experts
1.
Hwang, Y S
: 1 article (01/2001)
2.
Lefferts, P L
: 1 article (01/2001)
3.
Snapper, J R
: 1 article (01/2001)
Related Diseases
1.
Lung Diseases (Lung Disease)
05/01/1984 - "
Perilla ketone toxicity: a chemical model for the study of equine restrictive lung disease.
"
05/01/1984 - "
Perilla ketone was assessed for its usefulness as a model of equine restrictive pulmonary disease.
"
2.
Pulmonary Edema
11/01/1999 - "
To evaluate the effects of pulmonary edema induced by increased left atrial pressure (cardiogenic) and Perilla ketone (PK; noncardiogenic) on tracheal diameter in chronically instrumented awake sheep.
"
05/01/1993 - "
Perilla ketone (PK) is a potent lung toxin that causes increased microvascular permeability pulmonary edema in grazing animals.
"
11/01/1988 - "
Morphology of noncardiogenic pulmonary edema induced by Perilla ketone in sheep.
"
12/01/1987 - "
A model of increased microvascular permeability pulmonary edema was developed in chronically instrumented unanesthetized sheep using perilla ketone (PK).
"
12/01/1987 - "
Perilla ketone: a model of increased pulmonary microvascular permeability pulmonary edema in sheep.
"
3.
Lung Injury
03/01/1998 - "
Infusion of perilla ketone caused a significant pulmonary injury.
"
01/01/1994 - "
Evaluation of perilla ketone-induced unilateral lung injury using external gamma scanning.
"
01/01/1994 - "
We used a modified external gamma scanning technique to quantitate right and left lung permeability changes to iodinated sheep albumin before and after perilla ketone (PK)-mediated unilateral lung injury in seven anesthetized sheep.
"
4.
Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
03/01/1998 - "
Perilla ketone increases pulmonary microvascular permeability without changing filling pressures and is used to induce a model of human ARDS.
"
Related Drugs and Biologics
1.
Histamine (Histamine Dihydrochloride)
2.
Albumins
Related Therapies and Procedures
1.
Intravenous Administration
2.
Intravenous Infusions