glucose tolerance factor

organic cpd of low molecular wt (400-600); good source Saccharomyces cerevisiae; contains amino acids, trivalent chromium & nicotinic acid; chromium necessary; may be natural or synthetic

Also Known As:

Networked: 10 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Cohen, Revital: 1 article (01/2016)
2.	Dovrat, Ahuva: 1 article (01/2016)
3.	Eliaz, Anat: 1 article (01/2016)
4.	Mirsky, Nitsa: 1 article (01/2016)
5.	Bilo, Henk Jg: 1 article (04/2014)
6.	Houweling, Sebastiaan T: 1 article (04/2014)
7.	Kleefstra, Nanne: 1 article (04/2014)
8.	Landman, Gijs Wd: 1 article (04/2014)
9.	Abente, Federico Cuenca: 1 article (04/2006)
10.	Assalia, Ahmad: 1 article (04/2006)

Related Diseases

1.	Glucose Intolerance 01/01/1992 - "A new dietary factor, the glucose tolerance factor (GTF), was reported in 1957 that improved impaired glucose tolerance in rats. " 07/01/2004 - "Factor analysis revealed that variation of the 11 variables including serum level of leptin was affected by the three factors, i.e., the central factor associated with BMI, WHR, FTI, QUICKI and higher serum level of triglyceride (TG) and lower serum level of high-density lipoprotein-cholesterol (HDL-C), the glucose intolerance factor loaded with blood glucose level, FTI, QUICKI and higher serum level of TG (in women only) and the hypertension factor loaded with blood pressure and BMI (in men only), which could explain 62.0% and 66.7% of total variance in men and women, respectively, and higher serum level of TI and insulin resistance also loaded with both the central factor and glucose tolerance factor. "
2.	Colonic Neoplasms (Colon Cancer) 10/01/1996 - "Therefore, this rat LMCR model should be useful in studying human colonic cancer, especially in evaluating the therapeutic efficacy of anti-TAG72 immunoreagents such as the recombinant fusion proteins possessing the anti-TAG72 antibody fragment and the cytokine moiety."
3.	Adenocarcinoma 10/01/1996 - "In this study, we screened 6 animal tumor cell lines including 3 derived from mouse colonic adenocarcinomas (MCR-26, MCR-38-LD and CA-51), 1 from mouse ovarian adenocarcinoma (MOT), 1 from rat colonic adenocarcinoma LMCR, and 1 from rat mammalial adenocarcinoma (R3230AB) for TAG72 expression by using the B72.3 antibody. " 10/01/1996 - "Immunohistochemistry disclosed significant amounts of TAG72-expression in the dimethylhydrazine-induced BDIX rat colonic adenocarcinoma LMCR. " 10/01/1996 - "The rat TAG72 antigen purified from rat LMCR tumors showed strong immunoreactivity for the B72.3 antibody in ELISA analysis and displayed a smear band of high molecular weight in Western blotting, which is similar to the human TAG72 antigen purified from human LS174T colonic adenocarcinoma. "
4.	Neoplasms (Cancer) 10/01/1996 - "In addition, the iodinated B72.3 antibody was able to localize LMCR tumor in BDIX rats. " 04/01/2006 - "Ten minutes after LMCR, cells were injected into the peritoneal cavity, the 2 lateral trocars were removed and carbon dioxide insufflation was maintained for an additional 5 minutes to allow for tumor cell seeding. " 06/01/2005 - "Implantation of microencapsules containing VkCk/RM4-TNF-alpha cells into LMCR tumors in rats induced tumor regression as a result of tumor necrosis formation. " 11/01/2001 - "To better understand the role of STn antigen in tumor biology, we developed STn(+) (called LP) and STn(-) (called LN) clonal cell lines from a parental metastatic rat colon carcinoma cell line (LMCR). " 06/01/2005 - "The antigen-specific binding-reactivity of RM4/TNF-alpha for the TAG72 antigen was confirmed by immunohistochemical staining of rat LMCR tumor cells which expressed TAG72 antigen. "
5.	Insulin Resistance 04/15/2014 - "Chromium is considered to have positive effects on insulin sensitivity and is marketed as an adjunctive therapy for inducing glucose tolerance in cases of insulin resistance ("the glucose tolerance factor"). " 10/01/1999 - "Basal glucose (3.98 +/- 0.12 vs 3.94 +/- 0.11 mmol/L, hypertensive vs control subjects respectively), i.v. glucose tolerance factor KG (2.0 +/- 0.2 vs 2.2 +/- 0.1% min-1), SG (0.035 +/- 0.004 vs 0.032 +/- 0.007 min-1) and S1 [3.5 +/- 0.5 vs 3.8 +/- 0.3 10(4) min-1 (microU/mL)] were similar, both basal insulin and C-peptide exhibited a marked increase (87 +/- 8 vs 46 +/- 6 pmol/L, p = 0.0003; 637 +/- 62 vs 381 +/- 76 pmol/L, p < 0.03) demonstrating insulin resistance in basal conditions. " 07/01/2004 - "Factor analysis revealed that variation of the 11 variables including serum level of leptin was affected by the three factors, i.e., the central factor associated with BMI, WHR, FTI, QUICKI and higher serum level of triglyceride (TG) and lower serum level of high-density lipoprotein-cholesterol (HDL-C), the glucose intolerance factor loaded with blood glucose level, FTI, QUICKI and higher serum level of TG (in women only) and the hypertension factor loaded with blood pressure and BMI (in men only), which could explain 62.0% and 66.7% of total variance in men and women, respectively, and higher serum level of TI and insulin resistance also loaded with both the central factor and glucose tolerance factor. "

Related Drugs and Biologics

1.	Cytokines
2.	Recombinant Fusion Proteins
3.	Immunoglobulin Fragments
4.	B72.3 antibody
5.	Antigens
6.	Glucose (Dextrose)
7.	Leptin
8.	Tyrosine (L-Tyrosine)
9.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
10.	Triglycerides (Triacylglycerol)

Related Therapies and Procedures

1.	Therapeutics
2.	Surgical Instruments (Clip)