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glycineamide ribonucleotide

structure

Also Known As:

5'-phosphoribosylglycineamide; glycineamideribotide; 2-amino-(N-D-ribofuranosyl)acetamide 5'-phosphate

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Ribonucleotides: 307
    - glycineamide ribonucleotide: 3

Experts

1.	Assaraf, Yehuda G: 1 article (03/2007)

Related Diseases

1.	T-Cell Leukemia (Leukemia, T Cell) 09/15/1992 - "Metabolic effects and mode of cytotoxicity of 5-deazaacyclotetrahydrofolate (5-DACTHF, BW543U76), a glycineamide ribonucleotide transformylase inhibitor, were studied in MOLT-4 cells, a human T-cell leukemia line. " 09/15/1992 - "Metabolic effects and kill of human T-cell leukemia by 5-deazaacyclotetrahydrofolate, a specific inhibitor of glycineamide ribonucleotide transformylase."
2.	Colorectal Neoplasms (Colorectal Cancer) 03/01/2007 - "Recently, the novel antifolates raltitrexed and pemetrexed that target thymidylate synthase (TS) and glycineamide ribonucleotide transformylase (GARTF) were introduced for the treatment of colorectal cancer and malignant pleural mesothelioma. "
3.	Carcinoma (Carcinomatosis) 03/15/1994 - "We have investigated the potential of glycineamide ribonucleotide transformylase (GAR TFase) inhibitors to produce regressions in multiple preclinical models of colon carcinoma. "
4.	Malignant Mesothelioma 03/01/2007 - "Recently, the novel antifolates raltitrexed and pemetrexed that target thymidylate synthase (TS) and glycineamide ribonucleotide transformylase (GARTF) were introduced for the treatment of colorectal cancer and malignant pleural mesothelioma. "

Related Drugs and Biologics

1.	Hydroxymethyl and Formyl Transferases
2.	Phosphoribosylglycinamide Formyltransferase
3.	Thymidylate Synthase
4.	Folic Acid Antagonists
5.	Pemetrexed (MTA)
6.	raltitrexed (D 1694)