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thiocholchicine

RN refers to (S)-isomer

Also Known As:

thiocolchicine

Networked: 10 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Colchicine: 5157
    - thiocholchicine: 10

Experts

1.	Chambers, Timothy C: 1 article (06/2020)
2.	Huczyński, Adam: 1 article (06/2020)
3.	Jousheghany, Fariba: 1 article (06/2020)
4.	Klejborowska, Greta: 1 article (06/2020)
5.	Majcher-Uchańska, Urszula: 1 article (06/2020)
6.	Monzavi-Karbassi, Behjatolah: 1 article (06/2020)
7.	Moorjani, Anika: 1 article (06/2020)
8.	Piña-Oviedo, Sergio: 1 article (06/2020)
9.	Urbaniak, Alicja: 1 article (06/2020)
10.	Yuan, Youzhong: 1 article (06/2020)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1998 - "In this study the in vitro antitumor activity of a series of 20 colchicine analogues was tested and compared with colchicine and thiocolchicine on three different human cancer cell lines, two of which express the multidrug-resistance (MDR) phenotype. " 06/01/2020 - "To address this issue, a library of 17 novel COL derivatives, namely N-carbamates of N-deacetyl-4-(bromo/chloro/iodo)thiocolchicine, has been tested against two types of primary cancer cells. " 01/01/1957 - "[Problem of the use of antimitotic substances in chemotherapy of genital cancer: N-deacetyl-thiocolchicine (R 261)]." 01/01/1957 - "[Presentation of some demonstrative evidence on the results of tumor therapy by desoxyribonucleic acid and thiocolchicine; positive balance of desoxyribonucleic acid]."
2.	Myeloid Leukemia (Leukemia, Myelocytic) 09/21/1955 - "[Trial chemotherapy of myeloid leukemia by three new substances: demecolcine, thiocolchicine, myleran]."
3.	Penile Induration (Peyronie's Disease) 09/01/2016 - "The use of thiocolchicine in Peyronie's disease demonstrated improvement on penile curvature and reduction in plaque size. " 09/01/2016 - "A prospective, randomized, single - blind study comparing intraplaque injection of thiocolchicine and verapamil in Peyronie's Disease: a pilot study."
4.	Liver Neoplasms (Liver Cancer) 10/31/1961 - "[Treatment of primary cancer of the liver by N-desacetyl-thiocolchicine]."
5.	Lymphoid Leukemia 09/01/1985 - "Novel and known analogues of thiocolchicine were evaluated in vitro in a tubulin binding assay and in vivo in mice for acute toxicity and in the P388 lymphocytic leukemia assay. "

Related Drugs and Biologics

1.	Demecolcine
2.	Colchicine
3.	Busulfan (Busulfex)
4.	Tubulin
5.	Antimitotic Agents
6.	Verapamil (Calan)
7.	Methotrexate (Mexate)
8.	Carbamates
9.	Acids

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Therapeutics