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berbine

structure

Also Known As:

tetrahydroprotoberberine

Networked: 10 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Benzylisoquinolines: 151
    - Berberine Alkaloids: 9
      - berbine: 10
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - Berberine Alkaloids: 9
      - berbine: 10

Experts

1.	Chen, Weijiao: 2 articles (01/2022 - 10/2021)
2.	Cheng, Hao: 2 articles (01/2022 - 10/2021)
3.	Ge, Haixia: 2 articles (01/2022 - 10/2021)
4.	Xie, Yishi: 2 articles (01/2022 - 10/2021)
5.	Xu, Xiaojun: 2 articles (01/2022 - 10/2021)
6.	Xue, Hanyue: 2 articles (01/2022 - 10/2021)
7.	Yang, Peng: 2 articles (01/2022 - 10/2021)
8.	Yuan, Kai: 2 articles (01/2022 - 10/2021)
9.	Zhang, Jian: 2 articles (01/2022 - 10/2021)
10.	Zhang, Weitao: 2 articles (01/2022 - 10/2021)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 04/01/2021 - "The individual d- and l-enantiomers of the tetrahydroprotoberberine (THPB) d,l-govadine have been proposed for the treatment of cognitive deficiencies and positive symptoms of schizophrenia, respectively. " 02/15/2012 - "The tetrahydroprotoberberine natural product (±)-govadine has shown unique promise for the treatment of both the positive and negative symptoms of schizophrenia as it targets both dopamine D1 and D2 receptors. "
2.	Pain (Aches) 01/01/2018 - "In this study, we investigated whether and how CXCL1 contributes to vincristine-induced pain and the underlying mechanisms of levo-corydalmine (l-CDL, a tetrahydroprotoberberine). " 01/01/2020 - "In this study, we investigated a role for Nrf2/HO-1/CO in mediating vincristine-induced neuroinflammation by inhibiting connexin 43 (Cx43) production in the spinal cord following the intrathecal application of the HO-1 inducer protoporphyrin IX cobalt chloride (CoPP) or inhibitor protoporphyrin IX zinc (ZnPP), and we analyzed the underlying mechanisms by which levo-corydalmine (l-CDL, a tetrahydroprotoberberine) attenuates vincristine-induced pain. "
3.	Neuroinflammatory Diseases 01/01/2020 - "In this study, we investigated a role for Nrf2/HO-1/CO in mediating vincristine-induced neuroinflammation by inhibiting connexin 43 (Cx43) production in the spinal cord following the intrathecal application of the HO-1 inducer protoporphyrin IX cobalt chloride (CoPP) or inhibitor protoporphyrin IX zinc (ZnPP), and we analyzed the underlying mechanisms by which levo-corydalmine (l-CDL, a tetrahydroprotoberberine) attenuates vincristine-induced pain. "
4.	Hyperlipidemias (Hyperlipidemia) 01/15/2022 - "Corrigendum to "Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives to reduce SREBPs expression for the treatment of hyperlipidemia" [Eur. " 10/05/2021 - "Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives to reduce SREBPs expression for the treatment of hyperlipidemia." 11/01/2019 - "A novel series of tetrahydroprotoberberine derivatives (THPBs) were designed, synthesized, and evaluated as PCSK9 modulators for the treatment of hyperlipidemia. " 11/01/2019 - "Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia."
5.	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 10/27/2016 - "A novel series of tetrahydroprotoberberine derivatives (THPBs) were designed, synthesized, and evaluated as selective α1A-adrenergic receptors (AR) antagonists for the treatment of benign prostatic hyperplasia. "

Related Drugs and Biologics

1.	govadine
2.	Dopamine (Intropin)
3.	Vincristine (Oncovin)
4.	corydalmine
5.	Connexin 43 (Connexin43)
6.	Zinc
7.	protoporphyrin IX
8.	cobaltous chloride (cobalt(II)chloride)
9.	Alkaloids
10.	Benzylisoquinolines