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3-pyridinaldehyde

Also Known As:

nicotinaldehyde; 3-pyridinecarboxaldehyde

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aldehydes: 2153
  - 3-pyridinaldehyde: 3

Related Diseases

1.	Neoplasms (Cancer) 01/27/2023 - "The availability of nicotinaldehyde in a tumor environment fully blunts the antitumor activity of APO866 in vitro and in vivo. " 01/27/2023 - "This is the first study to report the role of nicotinaldehyde in the NAD-targeted anti-cancer treatment, highlighting the importance of the tumor metabolic environment in modulating the efficacy of NAD-lowering cancer therapy." 01/27/2023 - "Nicotinaldehyde, a Novel Precursor of NAD Biosynthesis, Abrogates the Anti-Cancer Activity of an NAD-Lowering Agent in Leukemia."
2.	Pulmonary Tuberculosis 11/01/1960 - "[Treatment of pulmonary tuberculosis with the combination of nicotinaldehyde-thiosemicarbazone and isoniazid. " 01/01/1959 - "[The association of nicotinaldehyde thiosemicarbazone and isoniazid in the treatment of pulmonary tuberculosis in adults]."
3.	Mitochondrial Diseases (Mitochondrial Disease) 01/27/2023 - "Nicotinaldehyde supplementation replenishes the intracellular NAD level in leukemia cells treated with NAMPT inhibitor APO866 and prevents APO866-induced oxidative stress, mitochondrial dysfunction and ATP depletion. "
4.	Leukemia 01/27/2023 - "Here, we report the identification of nicotinaldehyde as a novel precursor that can be used for NAD biosynthesis by human leukemia cells. " 01/27/2023 - "Nicotinaldehyde, a Novel Precursor of NAD Biosynthesis, Abrogates the Anti-Cancer Activity of an NAD-Lowering Agent in Leukemia." 01/27/2023 - "Nicotinaldehyde supplementation replenishes the intracellular NAD level in leukemia cells treated with NAMPT inhibitor APO866 and prevents APO866-induced oxidative stress, mitochondrial dysfunction and ATP depletion. "

Related Drugs and Biologics

1.	NAD (NADH)
2.	Thiosemicarbazones
3.	Isoniazid (Ftivazide)
4.	Adenosine Triphosphate (ATP)
5.	N- (4- (1- benzoylpiperidin- 4- yl)butyl)- 3- (pyridin- 3- yl)acrylamide

Related Therapies and Procedures

1.	Therapeutics