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N-methyllidocaine

RN given refers to chloride

Also Known As:

N-methyllidocaine bromide; N-methyllidocaine iodide; N-methyllidocaine methanesulfonate; W 49091; W-49091; methyl lidocaine; methyl-lidocaine

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - Anilides: 22
      - Acetanilides: 7
        Lidocaine: 9718
        N-methyllidocaine: 1
- Amides: 2428
  - Anilides: 22
    - Acetanilides: 7
      - Lidocaine: 9718
        N-methyllidocaine: 1

Related Diseases

1.	Ventricular Tachycardia 01/01/1988 - "When administered to animals developing only nonsustained ventricular tachycardia or no arrhythmias with programmed stimulation, methyl lidocaine administration enabled programmed stimulation to produce monomorphic sustained ventricular tachycardia in 10 of 13 experiments. " 01/01/1988 - "When administered to animals demonstrating sustained ventricular tachycardia (n = 6), methyl lidocaine (5 and 10 mg/kg i.v.) prevented the induction of the original ventricular tachycardia in 2 dogs, and in the remaining 4 dogs slowed the tachycardia (cycle length 163 +/- 18 ms vs. 198 +/- 11 and 219 +/- 11 ms, respectively, p less than 0.05). "
2.	Tachycardia (Tachyarrhythmias) 01/01/1988 - "When administered to animals demonstrating sustained ventricular tachycardia (n = 6), methyl lidocaine (5 and 10 mg/kg i.v.) prevented the induction of the original ventricular tachycardia in 2 dogs, and in the remaining 4 dogs slowed the tachycardia (cycle length 163 +/- 18 ms vs. 198 +/- 11 and 219 +/- 11 ms, respectively, p less than 0.05). "
3.	Myocardial Infarction 01/01/1988 - "Programmed electrical stimulation was used to evaluate the electrophysiologic and antiarrhythmic actions of methyl lidocaine in both conscious and anesthetized dogs, 4-7 days after myocardial infarction. " 01/01/1988 - "Antiarrhythmic and arrhythmogenic actions of methyl lidocaine during the recovery phase after canine myocardial infarction."
4.	Cardiac Arrhythmias (Arrythmia) 01/01/1988 - "The data suggest that the depression of conduction and prolonged refractoriness produced by methyl lidocaine in ischemically injured tissue may extinguish or slow some forms of ventricular arrhythmia while promoting the formation of new reentry pathways."