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carboranylalanine

has a 1,2-carborane cage in place of benzene ring of phenylalanine

Also Known As:

1,2-Dicarbadodecaborane(12)-1-propanoic acid, alpha-amino-, (S)-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Boron Compounds: 91
  - carboranylalanine: 2
Organic Chemicals: 133
- Boron Compounds: 91
  - carboranylalanine: 2
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Phenylalanine: 4090
      - carboranylalanine: 2
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Phenylalanine: 4090
        carboranylalanine: 2

Related Diseases

1.	Melanoma (Melanoma, Malignant) 10/01/1993 - "Penetration and binding of L- and D-carboranylalanine in human melanoma spheroids." 09/01/1995 - "The in vitro uptake of carboranylalanine (CBA) was evaluated using two cell lines, the human melanoma MRA 27, and the murine Harding-Passey melanoma. " 10/01/1993 - "Some boron compounds have recently been proposed for BNCT of malignant melanomas; the synthesized L- and D- forms of carboranylalanine and the previously tested compound L-p-boronophenylalanine are candidates. "
2.	Neoplasms (Cancer) 09/01/1995 - "o-Carboranylalanine (B10H10C2CH2CHNH2COOH) is a carborane-containing amino acid, which has been synthesized as a potential capture agent for boron neutron capture therapy (BNCT) of cancer. "
3.	Experimental Melanoma 09/01/1995 - "The in vitro uptake of carboranylalanine (CBA) was evaluated using two cell lines, the human melanoma MRA 27, and the murine Harding-Passey melanoma. "

Related Drugs and Biologics

1.	Boron Compounds
2.	Amino Acids
3.	4-boronophenylalanine

Related Therapies and Procedures

1.	Boron Neutron Capture Therapy