mezilamine

RN given refers to parent cpd; synonym O 6553 refers to HCl; structure

Also Known As:

2-methylamino-4-N-methylpiperazino-5-thiomethyl-6-chloropyrimidine; O 6553; mezilamine monohydrochloride; 2-pyridinamine, 4-chloro-N-methyl-6-(4-methyl-1-piperazinyl)-5-(methylthio)-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - mezilamine: 2

Related Diseases

1.	Dyskinesias (Dyskinesia) 01/01/1981 - "Mezilamine (0.3 mg/kg) also induced dyskinesias, which appeared to be less pronounced than those following haloperidol. " 01/01/1981 - "Acute dyskinesias in monkeys elicited by halopemide, mezilamine and the "antidyskinetic" drugs, oxiperomide and tiapride."
2.	Catalepsy 11/18/1981 - "The interaction of morphine with agents displaying antidopaminergic properties (low dose of apomorphine, alpha-methyl-p-tyrosine, the "classical" neuroleptic haloperidol as well as the "atypical" neuroleptics sulpiride, thioridazine, clozapine and mezilamine) has been studied both on locomotor activity in mice and catalepsy in rats. "

Related Drugs and Biologics

1.	Haloperidol (Haldol)
2.	Tiapride Hydrochloride
3.	alpha-Methyltyrosine (Metirosine)
4.	Antipsychotic Agents (Antipsychotics)
5.	Thioridazine (Mellaril)
6.	Sulpiride (neogama)
7.	Morphine (MS Contin)
8.	Clozapine (Clozaril)
9.	Apomorphine
10.	halopemide