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sudan yellow 3G
Also Known As:
4-phenylazo-1-phenyl-3-methyl-5-pyrazolone; C.I. 12,700; C.I. disperse yellow
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Azo Compounds: 333
sudan yellow 3G: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Pyrazoles: 61
Pyrazolones: 41
sudan yellow 3G: 1
Related Diseases
1.
Neoplasms (Cancer)
05/01/1982 - "
The incidence of these tumors was not significantly greater than that in controls; thus, the association between the administration of C.I. Disperse Yellow 3 and the stomach tumors in male rats is not clearly established.
"
05/01/1982 - "
However, because of the range of variability in the historical incidence of this tumor and because of the lack of a similar effect in male mice or in male and female rats, this increase was not regarded as being unequivocally related to the administration of C.I. Disperse Yellow 3. Under the conditions of this bioassay, C.I. Disperse Yellow 3 was considered to be carcinogenic for male F344 rats, causing an increased incidence of neoplastic nodules of the liver; this dye was not carcinogenic for female F344 rats.
"
2.
Carcinogenesis
05/01/1982 - "
A carcinogenesis bioassay of C.I. Disperse Yellow 3 (87.6% dye), a textile dye, was conducted by feeding diets containing 5,000 or 10,000 ppm of the test substance to groups of 50 F344 rats of either sex for 103 weeks.
"
3.
Liver Cell Adenoma (Hepatocellular Adenoma)
05/01/1982 - "
C.I. Disperse Yellow 3 was carcinogenic for female B6C3F1 mice, as evidenced by the increased incidence of hepatocellular adenomas; C.I. Disperse Yellow 3 was not carcinogenic for male B6C3F1 mice.
"
4.
Lymphoma (Lymphomas)
05/01/1982 - "
Thus, the incidence of alveolar/bronchiolar adenomas among males is not considered to be related to treatment with C.I. Disperse Yellow 3. Malignant lymphomas occurred in a dose-related (P<0.05) trend in female mice and at incidences greater (P<0.05) in the high-dose group than that in the controls (10/50; 16/50; 19/50).
"
05/01/1982 - "
Also, the increased incidence of malignant lymphoma in female mice may have been associated with the administration of C.I. Disperse Yellow 3. Levels of Evidence of Carcinogenicity: Male Rats: Positive Female Rats: Negative Male Mice: Negative Female Mice: Positive Synonyms: Disperse Fast Yellow 6; Acetamine Yellow CG
"
5.
Adenoma (Adenomas)
05/01/1982 - "
Thus, the incidence of alveolar/bronchiolar adenomas among males is not considered to be related to treatment with C.I. Disperse Yellow 3. Malignant lymphomas occurred in a dose-related (P<0.05) trend in female mice and at incidences greater (P<0.05) in the high-dose group than that in the controls (10/50; 16/50; 19/50).
"
Related Drugs and Biologics
1.
Coloring Agents (Dyes)
2.
yellow 6