octachlorostyrene

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

1.	Porphyrias (Porphyria) 03/01/1986 - "Distinction between octachlorostyrene and hexachlorobenzene in their potentials to induce ethoxyphenoxazone deethylase and cause porphyria in rats and mice." 06/30/1994 - "Influence of iron on the induction of hepatic tumors and porphyria by octachlorostyrene in C57BL/10ScSn mice." 03/01/1986 - "The potentials of octachlorostyrene (OCS) and hexachlorobenzene (HCB) to induce liver microsomal ethoxyphenoxazone deethylation (an indicator of induction of 3-methylcholanthrene and beta-naphthoflavone-like cytochrome P-450 monoxygenase activity) and cause porphyria in male C57BL/6 and C57BL/10 mice and female F344 rats were compared. "
2.	Hepatic Porphyrias (Hepatic Porphyria) 07/01/1999 - "The results indicated that occupational exposure to hexachlorobenzene and octachlorostyrene in aluminum degassing with hexachloroethane may affect porphyrin metabolism in a manner consistent with early secondary coproporphyrinuria-the first recognized step in the development of chronic hepatic porphyria. "
3.	Neoplasms (Cancer) 06/30/1994 - "Influence of iron on the induction of hepatic tumors and porphyria by octachlorostyrene in C57BL/10ScSn mice."
4.	Carcinoma (Carcinomatosis) 11/01/2022 - "Toxicity Assessment of Octachlorostyrene in Human Liver Carcinoma (HepG2) Cells."

1.	Hexachlorobenzene (HCB)
2.	beta-Naphthoflavone
3.	Porphyrins
4.	Methylcholanthrene
5.	Iron
6.	Indicators and Reagents (Reagents)
7.	Cytochrome P-450 Enzyme System (Cytochrome P450)
8.	Aluminum
9.	hexachloroethane