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4-methylumbelliferyl glucoside
RN given refers to (beta)-isomer
Also Known As:
4-MU-alpha-glucoside; 4-MU-glucoside; 4-methylumbelliferyl glucoside, (alpha)-isomer; 4-methylumbelliferyl-alpha-D-glucopyranoside; 4-methylumbelliferyl-beta-D-glucopyranoside; MUbetaGlu
Networked:
7
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Glycosides: 2119
Glucosides: 639
4-methylumbelliferyl glucoside: 7
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrans: 130
Benzopyrans: 195
Coumarins: 826
Umbelliferones: 3
Hymecromone: 123
4-methylumbelliferyl glucoside: 7
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzopyrans: 195
Coumarins: 826
Umbelliferones: 3
Hymecromone: 123
4-methylumbelliferyl glucoside: 7
Related Diseases
1.
Glycogen Storage Disease Type II (Pompe's Disease)
06/01/1978 - "
Pompe's disease: diagnosis in kidney and leucocytes using 4-methylumbelliferyl-alpha-D-glucopyranoside.
"
07/15/1977 - "
Diagnosis of Pompe's disease in cultured skin fibroblasts and primary amniotic fluid cells using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate.
"
07/15/1977 - "
The possible interference of neutral alpha-D-glucosidase in the diagnosis of Pompe's disease using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate for the assay of acid alpha-D-glucosidase was investigated.
"
03/01/1978 - "
Fibroblasts from patients with the adult, juvenile, and infantile form of glycogenosis type II (Pompe disease) were cultured under standardized conditions, and the activity of acid alpha-glucosidase (E.C.3.2.1.20) towards glycogen, maltose, and 4-methylumbelliferyl-alpha-D-glucopyranoside was measured.
"
01/01/1978 - "
Isoelectric precipitation at pH 5.0 and the use of the inhibitors, turanose, maltose and citrate, enabled the diagnosis of Pompe's disease to be made in dextran-isolated leucocytes using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate.
"
2.
Gaucher Disease (Gaucher's Disease)
01/01/1990 - "
We examined the property of beta-D-glucosidase in normal child liver, spleen and brain tissues and in tissues affected by Gaucher disease using two different kinds of synthetic substrates, 2-hexadecanoylamino-4-nitrophenyl-beta-D-glucopyranoside (HN Glc) and 4-methylumbelliferyl-beta-D-glucopyranoside (MU Glc).
"
09/01/1982 - "
The beta-glucosidase activity, as measured with 4-methylumbelliferyl-beta-D-glucopyranoside as the substrate, in the homogenates of brain from four cases of Gaucher's disease was less sensitive to inhibition by conduritol B epoxide (CBE) when compared with normal brain beta-glucosidase.
"
09/25/1980 - "
To date, enzymatic diagnosis of Gaucher's disease via a fluorometric assay procedure which utilizes 4-methylumbelliferyl-beta-D-glucopyranoside as a substrate has not been possible when liver serves as the source of enzyme since currently employed fluorometric procedures cannot adequately differentiate between a broad-specificity beta-glucosidase and lysosomal glucocerebrosidase activities in crude extracts of liver.
"
Related Drugs and Biologics
1.
Maltose
2.
Glucosidases
3.
beta-Glucosidase
4.
Acids
5.
Complex Mixtures
6.
Citric Acid (Citrate)
7.
Glycogen
8.
Glucosylceramidase (Glucocerebrosidase)
9.
Enzymes
10.
Dextrans (Dextran)