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propyl-N'-nitro-N-nitrosoguanidine
Also Known As:
PNNG; N'-nitro-N-nitroso-N-propylguanidine
Networked:
9
relevant articles (
0
outcomes,
3
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Nitroso Compounds: 446
Nitrosoguanidines: 2
Methylnitronitrosoguanidine: 1258
propyl-N'-nitro-N-nitrosoguanidine: 9
Amidines: 14
Guanidines: 29
Nitrosoguanidines: 2
Methylnitronitrosoguanidine: 1258
propyl-N'-nitro-N-nitrosoguanidine: 9
Related Diseases
1.
Metaplasia
06/08/1979 - "
Intestinal metaplasia was induced in the glandular stomachs of 25%, 75%, and 83% of the rats treated with PNNG for 4, 8, and 12 months, respectively.
"
06/01/1979 - "
[Sequential studies on experimental intestinal metaplasia and carcinoma in the stomach of rats by N-propyl-N'-nitro-N-nitrosoguanidine (author's transl)].
"
06/08/1979 - "
Intestinal metaplasia and adenocarcinoma induced in the stomach of rats by N-propyl-N'-nitro-N-nitrosoguanidine.
"
01/01/1979 - "
[Intestinal metaplasia and adenocarcinoma induced in the stomach of rats by N-propyl-N'-nitro-N-nitrosoguanidine (author's transl)].
"
09/01/1980 - "
Application of the methylene blue staining method to the study of experimentally PNNG-induced intestinal metaplasia of the canine stomach.
"
2.
Carcinoma (Carcinomatosis)
06/01/1979 - "
[Sequential studies on experimental intestinal metaplasia and carcinoma in the stomach of rats by N-propyl-N'-nitro-N-nitrosoguanidine (author's transl)].
"
01/01/1980 - "
Sequential studies on the histopathogenesis of gastric carcinoma in rats by a weak gastric carcinogen, N-propyl-N'-nitro-N-nitrosoguanidine.
"
01/01/1980 - "
Gastric carcinoma induced by PNNG seems to be more similar to human gastric cancer than that induced by MNNG.
"
3.
Stomach Neoplasms (Stomach Cancer)
02/01/1987 - "
Comparison of stomach cancer induced in rats by N-methyl-N'-nitro-N-nitrosoguanidine or N-propyl-N'-nitro-N-nitrosoguanidine.
"
01/01/1980 - "
Gastric carcinoma induced by PNNG seems to be more similar to human gastric cancer than that induced by MNNG.
"
11/01/1981 - "
N-Methyl-N-nitro-N-nitrosoquanidine, N-ethyl-N1-nitro-N-nitrosoguanidine, and N-propyl-N-nitro-N-nitrosoguanidine, which induce stomach cancer in rats, decreased the content of pepsinogen isoenzyme 1 )Pg 1), which was separated by poly-acrylamide gel electrophoresis.
"
01/01/1982 - "
Mutagens/carcinogens such as N-methyl-N'-nitro-soguanidine and N-propyl-N'-nitro-N-nitrosoguanidine can produce intestinal metaplasia in the glandular stomach of rats and gastric cancers.
"
4.
Adenocarcinoma
06/08/1979 - "
Intestinal metaplasia and adenocarcinoma induced in the stomach of rats by N-propyl-N'-nitro-N-nitrosoguanidine.
"
01/01/1979 - "
[Intestinal metaplasia and adenocarcinoma induced in the stomach of rats by N-propyl-N'-nitro-N-nitrosoguanidine (author's transl)].
"
5.
Neoplasms (Cancer)
02/01/1987 - "
The incidence of neoplasms of the glandular stomach was 18% with PNNG as compared to 65% with MNNG.
"
02/01/1987 - "
The incidence of forestomach tumors was high: 85% with MNNG, 64% with PNNG, but with PNNG a greater proportion of the forestomach neoplasms were benign.
"
Related Drugs and Biologics
1.
Carcinogens
2.
Methylene Blue (Methylthioninium Chloride)
3.
Methylnitronitrosoguanidine (MNNG)
4.
Pepsinogen A (Pepsinogen)
5.
Mutagens
6.
Isoenzymes