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isoxicam (Vectren)
Also Known As:
Vectren
; 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H- 1,2-benzothiazine-3-carboxamide-1,1-dioxide
Networked:
37
relevant articles (
7
outcomes,
9
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazines: 3
Piroxicam: 1149
isoxicam: 37
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Thiazines: 3
Piroxicam: 1149
isoxicam: 37
Experts
1.
Ehrich, Elliot W
: 1 article (08/2002)
2.
Emery, Paul
: 1 article (08/2002)
3.
Kong, Sheldon X
: 1 article (08/2002)
4.
Towheed, Tanveer E
: 1 article (08/2002)
5.
Watson, Douglas J
: 1 article (08/2002)
Related Diseases
1.
Rheumatoid Arthritis
10/18/1985 - "
The results of these studies confirm that isoxicam is clinically effective in the long-term treatment of patients with rheumatoid arthritis.
"
10/18/1985 - "
The results indicate that 200 mg of isoxicam once daily is effective for treating rheumatoid arthritis.
"
10/18/1985 - "
Three multicenter studies evaluating the long-term efficacy of isoxicam (Maxicam) were conducted in 745 patients with active classic or definite rheumatoid arthritis.
"
10/18/1985 - "
Long-term studies of isoxicam in the treatment of rheumatoid arthritis.
"
01/01/1987 - "
Nineteen patients, aged 60 years and over, with rheumatoid arthritis participated in a clinical trial to investigate the pharmacokinetics of isoxicam (a new non-steroidal anti-inflammatory drug) in this age group.
"
2.
Pain (Aches)
01/01/1986 - "
The isoxicam-treated group had a slightly greater mean pain score prior to treatment.
"
10/18/1985 - "
During a six-week, double-blind, placebo-controlled phase involving 176 patients, isoxicam at a dosage of 200 mg once daily was significantly superior to placebo in parameters (knee) of night pain, pain on walking, starting pain, pain on motion, swelling, tenderness, maximal extension, maximal flexion, and limitation of range of motion, and in the parameter (hip) of pain on walking.
"
02/23/1985 - "
Thirteen patients with osteo-arthritis entered a 12-month open-label assessment of the efficacy and safety of a single morning dose of isoxicam 200 mg. Pain scale scores were significantly reduced and this was accompanied by improvement in most of the symptoms.
"
01/01/1986 - "
2 Both isoxicam and piroxicam reduced pain and nocturnal awakening at days 5 and 10, but isoxicam was significantly superior to piroxicam in producing improvement in pain (at day 5, P less than 0.05) and in nocturnal awakenings (at day 10, P less than 0.05).
"
01/01/1986 - "
6 After 4 weeks, isoxicam given once daily in the morning was significantly more effective than naproxen given in the morning and the evening in relieving not only total pain as assessed by a visual analogue scale but, as importantly, night pain.
"
3.
Osteoarthritis
01/01/1986 - "
The pharmacokinetics of isoxicam, a new non-steroidal anti-inflammatory drug, were studied in 20 osteoarthritis patients with varying degrees of renal insufficiency.
"
01/01/1988 - "
Naproxen CR and isoxicam proved equally effective and well-tolerated for the treatment of osteoarthritis in this study.
"
01/01/1986 - "
7 This study indicates that isoxicam is an efficacious and well-tolerated once-daily NSAID for elderly patients with osteoarthritis.
"
01/01/1988 - "
Controlled-release naproxen compared with isoxicam in patients with osteoarthritis.
"
11/01/1984 - "
[Clinical evaluation of a new anti-inflammatory agent (Isoxicam) in osteoarthritis].
"
4.
Arthritis (Polyarthritis)
02/01/1985 - "
Clinical perspectives in rheumatology: a review of three common forms of arthritis and results of United States trials with isoxicam.
"
02/23/1985 - "
Isoxicam 200 mg once a day was effective and well tolerated in the long-term symptomatic treatment of osteo-arthritis.
"
02/23/1985 - "
A clinical evaluation of isoxicam in the treatment of osteo-arthritis.
"
03/01/1978 - "
Isoxicam at 25 mg/kg/day x 28 days significantly inhibited the multiple alterations with the developing polyarthritis.
"
02/23/1985 - "
Thirteen patients with osteo-arthritis entered a 12-month open-label assessment of the efficacy and safety of a single morning dose of isoxicam 200 mg. Pain scale scores were significantly reduced and this was accompanied by improvement in most of the symptoms.
"
5.
Diarrhea
07/01/1986 - "
In a study of protection against diarrhea induced by castor oil in rats, droxicam and piroxicam showed equal activity (ED50 = 0.081 and 0.079 mg/kg, p.o., respectively) and were 3.9 and 15.6 times more active than isoxicam and phenylbutazone, respectively.
"
Related Drugs and Biologics
1.
Piroxicam (Feldene)
2.
Naproxen (Naprosyn)
3.
Phenylbutazone (Butazolidin)
4.
Indomethacin (Indometacin)
5.
droxicam
6.
Aspirin (Acetylsalicylic Acid)
7.
Castor Oil (Oil, Castor)
8.
Tablets
9.
Nystatin (Mycostatin)
10.
Carrageenan
Related Therapies and Procedures
1.
Therapeutics