inositol pentaphosphate (inositol pentakisphosphate)

RN given refers to cpd without isomeric designation

Also Known As:

inositol pentakisphosphate; (D)-isomer, specified as 1,2,4,5,6 of inositol pentaphosphate; InsP5; inositol pentis(dihydrogen phosphate); myo-inositol 1,3,4,5,6-pentakisphosphate; myo-inositol pentakis(dihydrogen phosphate)

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Klein, Jon B: 2 articles (11/2018 - 09/2009)
2.	Merchant, Michael L: 2 articles (11/2018 - 09/2009)
3.	Rovin, Brad H: 2 articles (11/2018 - 09/2009)
4.	Benko-Iseppon, Ana M: 1 article (06/2021)
5.	Ferreira-Neto, José R C: 1 article (06/2021)
6.	Kido, Ederson A: 1 article (06/2021)
7.	Nepomuceno, Alexandre L: 1 article (06/2021)
8.	Pandolfi, Valesca: 1 article (06/2021)
9.	Rodrigues, Fabiana A: 1 article (06/2021)
10.	da Silva, Manassés D: 1 article (06/2021)

Related Diseases

1.	Diabetic Nephropathies (Diabetic Nephropathy) 11/01/2018 - "Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes." 09/01/2009 - "In renal biopsies from patients with early nephropathy from type 1 diabetes, we observed increased expression of inositol pentakisphosphate 2-kinase, which was present in granule-like cytoplasmic structures, and zona occludens 3. These results indicate that urinary peptide fragments reflect changes in expression of intact protein in the kidney, suggesting new potential mediators of diabetic nephropathy and candidate biomarkers for progressive renal function decline."
2.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/01/2018 - "Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes." 09/01/2009 - "In renal biopsies from patients with early nephropathy from type 1 diabetes, we observed increased expression of inositol pentakisphosphate 2-kinase, which was present in granule-like cytoplasmic structures, and zona occludens 3. These results indicate that urinary peptide fragments reflect changes in expression of intact protein in the kidney, suggesting new potential mediators of diabetic nephropathy and candidate biomarkers for progressive renal function decline."
3.	Vascular System Injuries 01/01/2019 - "The inositol phosphates, InsP5 and InsP6, have recently been identified as binding partners of fibrinogen, which is critically involved in hemostasis by crosslinking activated platelets at sites of vascular injury. "
4.	Starvation 05/19/2018 - "Here, using genetics and InsP profiling combined with Pi -starvation response (PSR) analysis in Arabidopsis thaliana, we showed that the kinase activity of inositol pentakisphosphate 2-kinase (IPK1), an enzyme required for phytate (inositol hexakisphosphate; InsP6 ) synthesis, is indispensable for maintaining Pi homeostasis under Pi -replete conditions, and inositol 1,3,4-trisphosphate 5/6-kinase 1 (ITPK1) plays an equivalent role. "
5.	Neuroblastoma 05/15/1991 - "The potential Ca2(+)-releasing activity of the inositol tetrakisphosphates Ins(1,3,4,6)P4 and DL-Ins(1,4,5,6)P4 and the inositol pentakisphosphate Ins(1,3,4,5,6)P5 and their effect on Ins(1,4,5)P3- and DL-Ins (1,3,4,5)P4-mediated Ca2+ release were examined in permeabilized SH-SY5Y human neuroblastoma cells. "

Related Drugs and Biologics

1.	Phosphotransferases (Kinase)
2.	Inositol (Myoinositol)
3.	Enzymes
4.	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
5.	CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase (CDP Diacylglycerol Inositol 3 Phosphatidyltransferase)
6.	1-Phosphatidylinositol 4-Kinase (1 Phosphatidylinositol 4 Kinase)
7.	Protein Tyrosine Phosphatases
8.	Biomarkers (Surrogate Marker)
9.	Proteins (Proteins, Gene)
10.	Phytic Acid (Inositol Hexaphosphate)

Related Therapies and Procedures

1.	Lasers (Laser)