ENNG

12/01/1982 - "[Studies on experimental gallbladder carcinoma with N-ethyl-N'-nitro-N-nitrosoguanidine in golden hamsters]."
11/01/1997 - "ACF and carcinoma were observed only in the interposed colon of ENNG-treated rats. "
09/01/1995 - "These results indicate that young animals may be more sensitive to ENNG than aged ones for induction of endometrial lesions, although ENNG-treatment alone is not sufficient for early and high induction of carcinomas even in young rats of this strain."
01/01/1991 - "Morphology and modes of cell proliferation in earliest signet-ring-cell carcinomas induced in canine stomachs by N-ethyl-N'-nitro-N-nitrosoguanidine."
02/01/1987 - "The numbers of metaplastic glands in groups I and III were higher than in group II. Gastric carcinomas were induced in all groups of rats treated with ENNG. "

06/01/1980 - "Chemotherapeutic study on canine gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine."
10/01/2001 - "We reported on suicide gene therapy in experimental gastric cancer induced by ENNG in the dog, and the results showed that in situ gene transfer of a suicide gene (Ad. "
09/01/1999 - "In situ gene transfer and suicide gene therapy of gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine in dogs."
01/01/1993 - "N-ethyl-N'-nitro-N-nitrosoguanidine induced stomach cancer earlier in monkeys with a low level of DNA repair enzyme, O6-alkylguanine-DNA alkyltransferase (AGT) in gastric mucosa. "
01/01/1990 - "Early gastric cancer induced by N-ethyl-N'-nitro-N-nitrosoguanidine in a cynomolgus monkey six years after initial diagnosis of the lesion."

10/01/1984 - "Endoscopic study of chronological changes leading to cancer in the esophagus of dogs induced by N-ethyl-N'-nitro-N-nitrosoguanidine."
02/01/2002 - "These findings suggest that OP has tumor-promoting effects on ENNG-treated endometrium of rats, possibly due to direct action on the uterus, as indicated by the uterotrophic effect when a high dose of OP was given. "
04/01/1991 - "In the mice given Mu-IFN, the incidence of duodenal tumors was significantly decreased (P less than 0.01), compared with that in mice given ENNG alone. "
06/01/1989 - "In this work, EGCG was found to inhibit tumor promotion in the gastrointestinal tract in a model system of mouse duodenal carcinogenesis with N-ethyl-N'-nitro-N-nitrosoguanidine. "
01/01/1982 - "ENNG significantly enhanced the tumor induction in the glandular stomach, while ENNG alone did not induce any tumors in the stomach. "

05/01/1993 - "Although limited doses of ENNG, such as those used in this study, have been reported to produce only undifferentiated adenocarcinomas, differentiated adenocarcinomas were found in seven of these 12 dogs. "
12/11/1998 - "In the control group treated with ENNG alone, various proliferative lesions were induced in the uterine endometrium and the incidence of endometrial adenocarcinomas was about 30%. "
10/01/1997 - "Thus, flat-type adenocarcinomas were induced in the dog colon by ENNG, and their development was followed by magnifying endoscopy."
08/16/1995 - "At the termination of the experiment (week 34 after the ENNG-treatment), 22% and 13% incidences of endometrial adenocarcinomas were observed in the experimental and control groups, respectively, the difference being without significance. "
08/16/1995 - "Induction of endometrial adenocarcinomas by a single intra-uterine administration of N-ethyl-N'-nitro-N-nitrosoguanidine to aged Donryu rats showing spontaneously persistent estrus."

10/01/1984 - "An endoscopical study of chronological change during the carcinogenetic process of cancer of the esophagus induced by N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG) in 16 male beagle dogs was performed to clarity whether or not precancerous lesions exist in the esophagus. "
10/01/1987 - "[Induction of canine gastric and esophageal cancers by N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG)]."