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bromfenacoum (Talon)

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Also Known As:

Talon; Ratak; brodifacoum; 3-(3-(4'-bromobiphenyl-4-yl)-1,2,3,4-tetrahydronaphth-1-yl)-4-hydroxycoumarin; Talon-G; WBA 8119; superwarfarin; 2H-1-Benzopyran-2-one, 3-(3-(4'-bromo(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-

Networked: 155 relevant articles (2 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- Pyrans: 5
  - Benzopyrans: 11
    - Coumarins: 240
      - 4-Hydroxycoumarins: 2
        bromfenacoum: 155
- 2-Ring Heterocyclic Compounds
  - Benzopyrans: 11
    - Coumarins: 240
      - 4-Hydroxycoumarins: 2
        bromfenacoum: 155

Experts

1.	Elliott, John E: 2 articles (07/2015 - 02/2010)
2.	Nadasdy, Tibor: 2 articles (01/2015 - 10/2011)
3.	Brodsky, Sergey V: 2 articles (01/2015 - 10/2011)
4.	Satoskar, Anjali A: 2 articles (01/2015 - 10/2011)
5.	Rovin, Brad H: 2 articles (01/2015 - 10/2011)
6.	Erdmann, Detlev: 2 articles (11/2014 - 06/2010)
7.	Shen, Min: 2 articles (02/2013 - 10/2012)
8.	Yan, Hui: 2 articles (02/2013 - 10/2012)
9.	Zhu, Lin: 2 articles (02/2013 - 10/2012)
10.	Xiang, Ping: 2 articles (02/2013 - 10/2012)

Related Diseases

1.	Poisoning 09/28/1998 - "None of the patients in our study died of superwarfarin poisoning. " 10/01/2015 - "Long-Acting Anticoagulant Rodenticide (Superwarfarin) Poisoning: A Review of Its Historical Development, Epidemiology, and Clinical Management." 07/01/2014 - "Most patients with superwarfarin poisoning did not exhibit any complication. " 01/01/2014 - "Superwarfarin poisoning and its management." 11/01/2013 - "Such impacts can arise either from primary poisoning when the non-target species ingest bait pellets containing toxicant or by secondary poisoning when the non-target species eats prey that has itself eaten brodifacoum. "
2.	Infection 11/01/2014 - "Secondary closure using the Sternal Talon was indicated for sternal nonunion or infection, or both, in all patients. " 11/01/2014 - "The data presented suggest that the osteosynthesis using the Sternal Talon device is a safe and effective modality for treating symptomatic sternal nonunion or acute dehiscence associated with infection (mediastinitis.)." 01/01/2012 - "We describe here (1) a method that details phospholipase D2 (PLD2) cloning in the pBac expression vector, (2) the large-scale infection of Sf21 insect cells for protein production, (3) protein purification by TALON cobalt metal affinity matrix and subsequent assessment of PLD2 protein and lipase activity, (4) application of purified PLD2 protein for the study of Rac2 GTPase biology involving GTP binding by a pull-down assay and GTP/GDP exchange activity, (5) a method of PLD2 expression that involves mammalian cells, (6) a physiological application as relates to adhesion, chemotaxis, and phagocytosis, and (7) a model that integrates the results of a PLD-GTPase interaction from the molecular to the physiological contexts."
3.	Hemorrhage 07/01/2015 - "The proportion of brodifacoum-exposed quail with hemorrhage was not correlated with liver residues, but was correlated with PT, suggesting that this assay is a useful indicator of avian anticoagulant rodenticide exposure. " 07/01/2015 - "50-fold prolongation of PT occurred at higher brodifacoum dosages and correlated to hemorrhage found at necropsy. " 01/01/2011 - "Patients rarely consult physicians before developing coagulopathy or bleeding in most reported cases of superwarfarin intoxication. " 09/01/2009 - "Since superwarfarin is popular and readily available in stores, it may cause intoxication or overexposure, which can result in coagulopathy or abnormal bleeding in humans and, thus, is an important public health problem. " 08/23/1993 - "On admission, the brodifacoum level was 731 micrograms/L and the patient suffered severe urinary tract hemorrhage, requiring transfusion of blood products. "
4.	Mediastinitis 11/01/2014 - "A consecutive series of 24 patients underwent Sternal Talon repair for sternal nonunion or acute mediastinitis, or both, after sternal wire closure. " 11/01/2014 - "The data presented suggest that the osteosynthesis using the Sternal Talon device is a safe and effective modality for treating symptomatic sternal nonunion or acute dehiscence associated with infection (mediastinitis.)."
5.	Supernumerary Tooth (Supernumerary Teeth) 10/01/2008 - "The prevalence of supernumerary teeth was significantly higher in children with true talon cusps as compared with the results of two previous general studies of Chinese children of similar age (P<0.05, Fisher's exact test). " 10/01/2014 - "This case report describes the clinical and radiographic features of talon cusp, dens invaginatus, shovel-shaped incisors and a supernumerary tooth occurring in a single patient, which is a rare presentation. " 10/01/2014 - "The fact that premaxilla is the predilection site for the occurrence of supernumerary teeth, talon cusp, dens invaginatus, and geminated teeth may suggest that the embryological development of premaxilla differ from other sites of the jaws. " 10/01/2014 - "Double talon cusps on supernumerary tooth fused to maxillary central incisor: Review of literature and report of case." 01/01/2014 - "Labial and palatal talon cusp on the maxillary supernumerary tooth in a deciduous dentition."

Related Drugs and Biologics

1.	Factor VIIa (Activated Factor VII)
2.	recombinant FVIIa (rFVIIa)
3.	GTP Phosphohydrolases (GTPases)
4.	Lipase (Acid Lipase)
5.	Guanosine Triphosphate (GTP)
6.	Guanosine Diphosphate (GDP)
7.	Cobalt
8.	phospholipase D2
9.	1-dodecylpyridoxal (PLD)
10.	bromfenacoum (Talon)

Related Therapies and Procedures

1.	Sternotomy
2.	Oral Medicine
3.	Homologous Transplantation (Allograft)
4.	Transplantation (Transplant Recipients)