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Ulcrux
for treatment of skin ulcers; contains heparin, allantoin, dexpanthenol
Also Known As:
Hepathrombin; Heparin, mixt. with (R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide and (2,5-dioxo-4-imidazolidinyl)urea
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Urea: 15015
Allantoin: 211
Ulcrux: 4
Imides: 79
Pantothenic Acid: 357
Ulcrux: 4
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Imidazoles: 150
Imidazolidines: 39
Hydantoins: 306
Allantoin: 211
Ulcrux: 4
Pharmaceutical Preparations
Drug Combinations: 5337
Ulcrux: 4
Carbohydrates: 22023
Polysaccharides: 15383
Glycosaminoglycans: 5640
Heparin: 24996
Ulcrux: 4
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Alanine: 4133
beta-Alanine: 172
Pantothenic Acid: 357
Ulcrux: 4
Related Diseases
1.
Thrombosis (Thrombus)
01/01/1984 - "
The studies also demonstrate the only local thrombolytic effect of the Hepathrombin ointments because the thrombus of the right ear, always treated with ointment base only, did not show any change in length as contrasted to that of the left ear of the same animal treated with the Hepathrombin ointments.
"
2.
Pain (Aches)
01/01/1983 - "
The pain score decreased from 12 to 7. The superiority of Hepathrombin-Salbe over the ointment base could be statistically demonstrated; the difference between the two groups was significant with respect to swelling after just one day, and with respect to joint mobility after just 2 days of treatment.
"
01/01/1983 - "
In the Hepathrombin group, swelling subsided continuously from 100 to 42% and the pain score decreased from 12 to 3. With application of the ointment base, swelling increased at first to 114% after 2 days, then decreased until Day 8 to 86% of the initial value.
"
3.
Erythema
01/01/1982 - "
The inhibition of UV-erythema by Hepathrombin underlines the rapid skin penetration of the active substances.
"
01/01/1982 - "
The antiinflammatory effect of Hepathrombin is also discussed in connection with the mechanism of UV-induced erythema.
"
01/01/1982 - "
Compared to the ointment base, the application of a heparin-allantoin-dexpanthenol combination ointment (Hepathrombin ointment) to guinea pigs immediately after as well as 30 and 120 min prior to UV-irradiation effects more rapid regression of the erythema along with a reduction in erythema formation.
"
4.
Anaphylaxis (Anaphylactic Shock)
01/01/1984 - "
Local application of a heparin-allantoin-dexpanthenol (Hepathrombin-Adenylchemie) ointment to rats 15 min prior to induction of a passive cutaneous anaphylaxis (PCA) reaction inhibits the anaphylactic reaction as compared to the ointment base.
"
Related Drugs and Biologics
1.
Ointments (Pastes)
2.
Heparin (Liquaemin)
3.
Allantoin
4.
dexpanthenol (panthenol)