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tropatepine

structure

Also Known As:

3-dibenzo(b,e)thiepin-11(6H)-ylidene- 1 alpha H,5 alpha H-tropane; Lepticur; 3-dibenzo(b,e)thiepin-11(6H)-ylidene-8-methyl-8-azabicyclo(3.2.1) octane

Networked: 8 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiepins
    - Dibenzothiepins
      - tropatepine: 8
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Dibenzothiepins
      - tropatepine: 8

Experts

1.	Arnulf, Isabelle: 1 article (01/2021)
2.	Leu-Semenescu, Smaranda: 1 article (01/2021)
3.	Nigam, Milan: 1 article (01/2021)
4.	Briet, Jeanne: 1 article (09/2017)
5.	Corneloup, Marie: 1 article (09/2017)
6.	D'Athis, Philippe: 1 article (09/2017)
7.	Heitzmann, Edwige: 1 article (09/2017)
8.	Javelot, Hervé: 1 article (09/2017)
9.	Lameira, Catherine: 1 article (09/2017)
10.	Vailleau, Jean-Louis: 1 article (09/2017)

Related Diseases

1.	Parkinsonian Disorders (Parkinsonism) 01/01/2021 - "In this case report, we describe three patients with severe, drug-resistant cataplexy who experienced a dramatic improvement when treated with tropatepine, an anticholinergic muscarinic antagonist (commonly used to prevent neuroleptic-induced parkinsonism) after the usual treatments had failed. "
2.	Cataplexy 01/01/2021 - "Successful treatment of drug-resistant cataplexy with the anticholinergic drug tropatepine." 01/01/2021 - "In this case report, we describe three patients with severe, drug-resistant cataplexy who experienced a dramatic improvement when treated with tropatepine, an anticholinergic muscarinic antagonist (commonly used to prevent neuroleptic-induced parkinsonism) after the usual treatments had failed. "
3.	Parkinson Disease (Parkinson's Disease) 01/01/1982 - "Study of the action of tropatepine in 25 cases of Parkinson's disease and 5 post-neuroleptic syndromes. " 07/01/1989 - "Effect of tropatepine, an anticholinergic drug, on regional cerebral blood flow in patients with Parkinson's disease."
4.	Xerostomia 09/01/2017 - "The most frequently prescribed drugs were cyamemazine (n=1429; 20%) and tropatepine (n=1403; 19%), two drugs marketed almost exclusively in France and with a score of 3. The frequency of patients with a high AIS score, greater than 5, was significantly higher in patients who received laxatives and treatments of xerostomia. "
5.	Tremor (Tremors) 01/01/1976 - "In comparison to the activity of the other synthetic antiparkinson drugs, the activity of tropatepine hydrochloride is: -- similar on akineto-hypertonia and on tremor; -- better on akathisia and, though less frequently, on anormal dyskinetic movements due to long term neuroleptic treatment. "

Related Drugs and Biologics

1.	Antipsychotic Agents (Antipsychotics)
2.	Cholinergic Antagonists (Anticholinergics)
3.	Muscarinic Antagonists
4.	Antiparkinson Agents (Antiparkinsonian Agents)
5.	pyrodifenium bromide (prifinium bromide)
6.	cyamemazine