tetrahydroaldosterone

08/01/2023 - "Tetrahydroaldosterone is the most abundant metabolite and the most reliable for the diagnosis of primary aldosteronism, but it is not commonly measured."
06/01/2006 - "Similarly, urinary tetrahydroaldosterone had higher sensitivity in hypokalaemic than in normokalaemic primary aldosteronism (sensitivity 64% vs 36%, specificity 100%), whereas for aldosterone-18-glucuronide, no differences in hypo- and normokalaemic primary aldosteronism were found (sensitivity 45% and 43%, specificity 100%). "
07/01/2003 - "Urinary tetrahydroaldosterone as a screening method for primary aldosteronism: a comparative study."
02/01/1986 - "The tetrahydroaldosterone/21-deoxytetrahydroaldosterone ratio varied more in patients with primary aldosteronism than in control subjects. "
01/01/1985 - "However, in several patients with primary aldosteronism even the tetrahydroaldosterone values remained in the normal range. "

02/01/1995 - "In the present study the aldosterone-18-glucuronide and tetrahydroaldosterone values in 24 hour urine collections of healthy nonpregnant women, women with normal pregnancies and women with pregnancy induced hypertension (PIH) were compared. "

06/01/1985 - "The study showed that weight loss during the ten month period was accompanied by a significant decrease in urinary aldosterone, tetrahydroaldosterone -3-glucuronide and plasma renin activity values. "

05/01/1969 - "[Studies on aldosterone in obesity; urinary excretion of aldosterone and tetrahydroaldosterone]."

12/01/1986 - "Transient but significant increases in urinary tetrahydroaldosterone excretion and plasma cortisol concentration were observed as hypercalcemia and hypertension developed. "
02/01/1985 - "We suggest that in those cases of hypertension and suspected primary aldosteronism when aldosterone-18-glucuronide and tetrahydroaldosterone glucuronide values remain within normal range, determination of the free metabolite fraction may be diagnostically helpful."
09/01/1980 - "The effects of a continuous 5-day ACTH infusion (40 units/24 hr) on plasma aldosterone (aldo) concentration and urinary excretion of aldosterone pH 1 conjugate, tetrahydroaldosterone and free aldo were investigated in 6 normotensive children, and 7 children with hypertension of unknown origin. "