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pinaverium

RN given refers to parent cpd; structure
Also Known As:
4-(6-bromoveratryl)-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)morpholinium bromide; Dicetel; Eldicet; pinaverium bromide; morpholinium, 4-((2-bromo-4,5-dimethoxyphenyl)methyl)-4-(2-(2-(6,6-dimethylbicyclo(3.1.1)hept-2-yl)ethoxy)ethyl)-
Networked: 75 relevant articles (14 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Geng, Hao: 4 articles (08/2021 - 01/2017)
2. Lu, Jin: 4 articles (08/2021 - 01/2017)
3. Chen, Hong: 4 articles (02/2018 - 12/2012)
4. Gao, Song: 4 articles (02/2018 - 12/2012)
5. Ding, Min: 3 articles (08/2021 - 01/2020)
6. Guo, Jing: 3 articles (08/2021 - 01/2020)
7. Liu, Lian: 3 articles (08/2021 - 01/2020)
8. Pei, Li-Xia: 3 articles (08/2021 - 08/2012)
9. Fan, Heng: 3 articles (01/2021 - 07/2015)
10. Huang, Dawei: 3 articles (01/2021 - 07/2015)

Related Diseases

1. Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
2. Abdominal Pain (Pain, Abdominal)
11/01/2017 - "Primary end points were significantly greater reductions in abdominal pain and Bristol stool score (before vs after the 4-week study period) in patients given tongxie compared with patients given placebo or pinaverium. "
01/01/2021 - "OR was 3.43 (2.00-5.88, p < 0.0001), and NNT was 4. Pinaverium also demonstrated a beneficial treatment effect for abdominal pain, stool change, and bloating improvement or resolution. "
02/28/1999 - "Administration of pinaverium bromide completely released in 6 and significantly improved the abdominal pain in other 12 patients, while the bloating disappeared in 12 and was significantly improved in 5 from 22 patients. "
03/20/2017 - "Administration of pinaverium bromide alone one day before examination was beneficial to relieve symptoms of abdominal pain during nonanesthetic colonoscopy. "
01/01/2023 - "The mean severity scores of abdominal pain were 1.39 ± 1.28, 0.97 ± 1.43 versus 2.91 ± 1.44 (p < 0.0001) in P or PB + P group versus PB group at week 2 and were 0.90 ± 1.21, 1.28 ± 1.87 versus 2.74 ± 1.75 (p < 0.0001) at week 4. The mean frequency scores were 2.55 ± 2.55, 2.03 ± 2.80 versus 5.12 ± 2.09(p < 0.0001) in P or PB + P group versus PB group at week 2 and were 1.72 ± 2.46, 2.00 ± 2.90 versus 4.55 ± 2.55 (p < 0.0001) at week 4. When comparing the changes in SSS, PHQ-15, and GAD-7 scores, patients accepting pregabalin or pregabalin combination regimen reported a more decrease than pinaverium bromide recipients (p = 0.0002, p = 0.0002, and p = 0.0033). "
3. Diarrhea
4. Pain (Aches)
5. Constipation

Related Drugs and Biologics

1. Simethicone
2. Tablets
3. melitracen drug combination flupentixol
4. Therapeutic Uses
5. alverine
6. eluxadoline
7. drotaverin (No-spa)
8. Anti-Anxiety Agents (Anxiolytics)
9. Endotoxins
10. Antidepressive Agents (Antidepressants)

Related Therapies and Procedures

1. Acupuncture Points (Acupuncture Point)
2. Moxibustion
3. Catgut
4. Oral Administration
5. Therapeutics