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alborixin

polycyclic, polyether, acidic, ionophore antibiotic; RN given refers to cpd with stereoisomeric designation; structure in sixth source

Also Known As:

alborixin monopotassium salt

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - alborixin: 3

Experts

1.	Ali, Shiekh Abid: 1 article (08/2016)
2.	Hamid, Abid: 1 article (08/2016)
3.	Hussain, Aehtesham: 1 article (08/2016)
4.	Kumar, Ajay: 1 article (08/2016)
5.	Makhdoomi, Ubaid Sharif: 1 article (08/2016)
6.	Mushtaq, Saleem: 1 article (08/2016)
7.	Qazi, Asif Khurshid: 1 article (08/2016)
8.	Qazi, Parvaiz H: 1 article (08/2016)
9.	Rehman, Shakeel-U: 1 article (08/2016)
10.	Shah, Aabid Manzoor: 1 article (08/2016)

Related Diseases

1.	Carcinoma (Carcinomatosis) 08/25/2016 - "Alborixin displayed the maximum cytotoxic activity against HCT-116 human colon carcinoma cells and therefore further studies were carried on this cell line. "
2.	Weight Loss (Weight Reduction) 04/01/1995 - "Some toxicity, as demonstrated by weight loss, was observed with both maduramicin and alborixin. "
3.	Weight Gain 02/01/1987 - "Alborixin is similar to many other polyethers in that weight gains are adversely affected at drug levels essential for solid broad-spectrum anticoccidial activity." 02/01/1987 - "Higher concentrations of alborixin (greater than 50 ppm) appear essential to achieve broad-spectrum and comparable anticoccidial activity, however, these levels substantially depressed weight gains. " 02/01/1987 - "Alborixin, a polyether antibiotic with ionophore properties, was evaluated to determine the effect of the drug on weight gain of chickens and to define the anticoccidial spectrum of activity. "
4.	Neoplasms (Cancer) 08/25/2016 - "Isolation and characterization of alborixin from Streptomyces scabrisporus: A potent cytotoxic agent against human colon (HCT-116) cancer cells."
5.	Cryptosporidiosis 04/01/1995 - "Evaluation of maduramicin and alborixin in a SCID mouse model of chronic cryptosporidiosis." 04/01/1995 - "Two polyether ionophores, maduramicin and alborixin, were evaluated for anticryptosporidial activity in a severe combined immune deficient (SCID) mouse model of cryptosporidiosis. "

Related Drugs and Biologics

1.	Ionophores
2.	Cytotoxins (Cytolysins)
3.	Antineoplastic Agents (Antineoplastics)
4.	Anti-Bacterial Agents (Antibiotics)
5.	Polyether Polyketides
6.	maduramicin