sulfomucin

05/01/1985 - "This faecal sulphatase activity may be involved in the degradation of colonic mucus and merits further study but these findings do not explain the relative depletion of colonic mucosal sulphomucins in ulcerative colitis."
05/01/2008 - "Sulphomucin expression is increased in the mucous gel layer of the ulcerative colitis pouch compared with that of the familial adenomatous polyposis pouch. "
05/01/1985 - "Histochemical studies have shown a relative depletion of colonic sulphated mucins (sulphomucins) in active ulcerative colitis. "
05/01/2008 - "High-iron-diamine positivity (i.e., sulphomucin expression) was greater in ulcerative colitis pouch mucous gel (2.083 +/- 0.5 vs. 0.556 +/- 0.4, P = 0.003). "
05/01/2008 - "Sulphomucin expression in ileal pouches: emerging differences between ulcerative colitis and familial adenomatous polyposis pouches."

06/01/2005 - "Moreover, there were foci of adenosis adjacent to the adenocarcinoma foci, which also did not contain sulfomucin. "
11/01/1989 - "Sulfomucin-containing goblet cells were also found in the inflammatory lesions biopsied from the ileal stomas of both patients, as well as from the adenocarcinoma found in one patient. "
04/01/1989 - "IM secreting sulphomucins was seen to be associated with gastric adenocarcinoma."
10/01/1988 - "Adenocarcinomas had a sulphomucin or mixed secretion pattern with transitional features in the adjacent mucosa mucosa (18/27). "
09/01/1986 - "In the columnar lined oesophagus sulphomucin production is common and its presence does not help to identify those individuals at particular risk of developing an adenocarcinoma."

01/01/1996 - "No significant change was demonstrated in the mean sulfomucin staining score comparing normal and colon cancer patients. "
04/01/1995 - "We studied mucin production in the unsectioned colon, demonstrating that ACFs producing sulphomucins (like the normal distal rat colon) were progressively reduced when ACF multiplicity increased, whereas ACFs containing sialomucins (correlated with an increased risk of colon cancer) or both sulphomucins and sialomucins increased with crypt multiplicity. "
01/01/1996 - "To establish patterns of mucin staining in the colon, a differential staining method was developed separating acid mucins into sialomucins and sulfomucins, and their distribution was studied along the colon of 9 normal subjects, 6 patients with ulcerative colitis in remission and 9 with colon cancer. "

04/01/1990 - "The purpose of this study has been to determine the prevalence of intestinal metaplasia (IM) and its subtypes in normal, benign and malignant states, with special reference to the significance of presence as well as location of sulphomucins in the metaplastic epithelium. "
06/01/1984 - "In a previous study of CELO an incompletely differentiated variant of intestinal metaplasia secreting sulphomucins (type II B) was found. "
05/01/2008 - "Histological specimens were examined according to the updated Sydney system and the ones with incomplete intestinal metaplasia were further stained for sulphomucin visualisation to divide these into types II and III. The overall prevalence of intestinal metaplasia was 19%. "
11/01/2005 - "The incomplete intestinal metaplasia (IM) that is reported to be a risk factor for gastric carcinogenesis in man usually features sulfomucin production and thus is considered of colonic type. "
01/01/2004 - "The area covered by incomplete type of intestinal metaplasia and the proportion of sulfomucins were significantly higher in the esophagus than in the stomach. "

07/15/1985 - "In contrast with other studies, carcinomas in young people were found to produce larger amounts of sulphomucins than those occurring in older people. "
03/01/1999 - "We have studied the biological properties of LS174T human colon carcinoma cells before and after suppression of sulfomucin production. "
03/01/1999 - "Although the loss of sulfomucins was known as an indicator of carcinogenesis and malignant progression of colonic epithelia, it was not known whether the loss was directly related to the malignant behavior of colon carcinoma cells. "
03/01/1999 - "Malignant and other properties of human colon carcinoma cells after suppression of sulfomucin production in vitro."
07/01/1998 - "High sulphomucin positivity in the metaplastic epithelium is only seen in intestinal-type carcinomas, although in a small number of cases (21.5%). "