alpha-tocopherol phosphate

RN given refers to (2R*(4R*,8R*))-(+-)-isomer

Also Known As:

alpha-tocopherol phosphate, disodium salt (2R*(4R*,8R*))-(+-)-isomer; alpha-tocopherol phosphate, sodium salt (2R-(2R*(4R*,8R*)))-isomer; alpha-tocopheryl phosphate; alpha-tocopherylphosphate; sodium alpha-tocopherol phosphate; tocopheryl phosphate

Networked: 15 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Vitamin E: 8680
        Tocopherols: 1861
        alpha-Tocopherol: 2941
        alpha-tocopherol phosphate: 15
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Vitamin E: 8680
        Tocopherols: 1861
        alpha-Tocopherol: 2941
        alpha-tocopherol phosphate: 15

Experts

1.	Libinaki, Roksan: 3 articles (05/2010 - 12/2004)
2.	Ogru, Esra: 3 articles (05/2010 - 12/2004)
3.	Azzi, Angelo: 3 articles (09/2008 - 12/2004)
4.	Gianello, Robert: 2 articles (06/2006 - 12/2004)
5.	Zingg, Jean-Marc: 2 articles (06/2006 - 12/2004)
6.	Hama, Susumu: 1 article (02/2022)
7.	Kirimura, Naoko: 1 article (02/2022)
8.	Kogure, Kentaro: 1 article (02/2022)
9.	Obara, Aki: 1 article (02/2022)
10.	Takatsu, Hirokatsu: 1 article (02/2022)

Related Diseases

1.	Myocardial Infarction 09/01/2008 - "The tocopheryl phosphate fed rats exhibited significant cardioprotection as evidenced by improved ventricular performance and reduced myocardial infarct size and cardiomyocyte apoptosis. "
2.	Rheumatoid Arthritis 02/20/2022 - "Tocopheryl Phosphate Inhibits Rheumatoid Arthritis-Related Gene Expression In Vitro and Ameliorates Arthritic Symptoms in Mice."
3.	Ischemia 01/01/1991 - "The effects of phosphocreatine and tocopheryl phosphate and their combined use in ischemia and reperfusion of the heart were studied in anesthetized dogs. " 01/01/1989 - "[Improving the contractility and metabolism of the isolated rat heart during post-ischemia reperfusion with phosphocreatine, tocopheryl phosphate and their combination]." 09/01/2008 - "The results of this study demonstrated for the first time that tocopheryl phosphate could ameliorate myocardial ischemic reperfusion injury by converting ischemia/reperfusion-mediated death signal into a survival signal by modulating MAP kinase signaling." 01/01/1991 - "[Phosphocreatine, tocopheryl phosphate and their combination in acute ischemia and myocardial reperfusion in dogs: the effect on rhythm disorders, left ventricle contractility and infarct size]."
4.	Atherosclerosis 05/01/2010 - "Effect of tocopheryl phosphate on key biomarkers of inflammation: Implication in the reduction of atherosclerosis progression in a hypercholesterolaemic rabbit model." 06/01/2006 - "The effect of tocopheryl phosphate on atherosclerosis progression has been studied in rabbits, fed with a 2% cholesterol diet and compared with an equivalent amount of alpha-tocopheryl acetate. " 05/01/2010 - "2. The present study examined the effectiveness of a novel tocopheryl phosphate mixture (TPm) compared with that of alpha-tocopherol (TA) on key pro-inflammatory markers involved in atherogenesis, including interleukin (IL)-1beta, IL-6, IL-8, plasminogen activator inhibitor-1, tumour necrosis factor-alpha and C-reactive protein (CRP), as well as vascular function and lesion development in rabbits fed a 2% cholesterol diet. "
5.	Myocardial Reperfusion Injury 09/01/2008 - "The results of this study demonstrated for the first time that tocopheryl phosphate could ameliorate myocardial ischemic reperfusion injury by converting ischemia/reperfusion-mediated death signal into a survival signal by modulating MAP kinase signaling."

Related Drugs and Biologics

1.	alpha-Tocopherol
2.	Oxycodone (Oxycontin)
3.	Cholesterol
4.	Interleukin-8 (Interleukin 8)
5.	Interleukin-6 (Interleukin 6)
6.	Plasminogen Activators (Plasminogen Activator)
7.	Phosphotransferases (Kinase)
8.	Interleukins
9.	C-Reactive Protein
10.	Analgesics (Analgesic Drugs)

Related Therapies and Procedures

1.	Therapeutics