7-oxo-7-thiomethoxyxanthone-2-carboxylic acid

inhibits allergen-induced bronchospasm; structure; RN given refers to Na salt

Also Known As:

7-oxo-7-thiomethoxy-xanthone-2-carboxylic acid; RS 7540; RS-7540; 9H-Xanthene-2-carboxylic acid, 7-(methylsulfinyl)-9-oxo-, sodium salt

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Exercise-Induced Asthma (Asthma, Exercise Induced) 04/01/1978 - "Ten of these subsequently received a dose of 20 mg. RS 7540 at both dose levels had a statistically significant effect in giving total or partial protection from exercise-induced bronchospasm; however, no dose relationship was apparent." 04/01/1978 - "The effect of inhaled RS 7540, a xanthone, on exercise-induced asthma." 04/01/1978 - "The effect of 71 oxo-7-thiomethoxyxanthone-2-carboxylic acid sodium salt (RS 7540) in inhibiting exercise-induced asthma was compared with that of placebo in a double-blind crossover study. "
2.	Asthma (Bronchial Asthma) 01/01/1982 - "These differences suggest that RS 7540 has major deficiencies as a potential alternative to DSCG in the treatment of bronchial asthma."