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oxadiazon

manufactured by the Societe Rhone-poulenc, France; structure

Also Known As:

2-(tert-butyl)-4-(2,4-dichloro-5-isopropyloxy-phenyl) delta(2)-1,3,4-oxadiazoline-5-one; Ronstar

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - Oxadiazoles: 146
        oxadiazon: 10

Experts

1.	Cao, Zigang: 1 article (10/2020)
2.	Chen, Xiaobei: 1 article (10/2020)
3.	Freigang, Jörg: 1 article (10/2020)
4.	Gille, Sascha: 1 article (10/2020)
5.	Huang, Yong: 1 article (10/2020)
6.	Jiang, Ping: 1 article (10/2020)
7.	Kahlau, Sabine: 1 article (10/2020)
8.	Kleeßen, Sabrina: 1 article (10/2020)
9.	Klie, Sebastian: 1 article (10/2020)
10.	Laber, Bernd: 1 article (10/2020)

Related Diseases

1.	Porphyrias (Porphyria) 10/01/1997 - "Administration of oxadiazon or oxyfluorfen (1000 ppm in the diet) to male BALB/c mice for 9 days resulted in experimental porphyria, resembling the acute phase of human variegate porphyria. " 07/01/2001 - "These data demonstrate that administration of tiagabine or topiramate to oxadiazon-treated animals can provoke a condition resembling an acute porphyric attack and suggest that administration of these drugs to patients with suspected porphyria should be avoided. " 02/01/2016 - "Oxadiazon (OX) is a protoporphyrinogen oxidase-inhibiting herbicide that induces porphyria and liver tumors in rodents. "
2.	Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency) 10/01/1997 - "Administration of oxadiazon or oxyfluorfen (1000 ppm in the diet) to male BALB/c mice for 9 days resulted in experimental porphyria, resembling the acute phase of human variegate porphyria. " 07/01/2001 - "Administration of the protoporphyrinogen oxidase inhibitor oxadiazon (12.5 mg/kg/day) for four days to male Wistar rats caused a partial block of porphyrin biosynthesis, thus mimicking the condition of quiescent variegate porphyria. "
3.	Cardiotoxicity 10/01/2020 - "Exposure to Oxadiazon-Butachlor causes cardiac toxicity in zebrafish embryos."
4.	Dyslipidemias (Dyslipidemia) 01/01/2024 - "We found positive associations of obesity with hexachlorobenzene (HCB), β-hexachlorocyclohexane (β-HCH) and chlorpyrifos, diabetes with pentachlorophenol (PCP), fipronil and fipronil sulfone, hypertension with PCB180 and chlorpyrifos, and dyslipidemia with diflufenican and oxadiazon, among others. "
5.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2019 - "Taken together, our findings reveal for the first time that oxadiazon could exert neurotoxic effects by impairing differentiative capabilities of primary neuronal cells and indicate that ALDH2 and ACYP2 are relevant molecular targets for the neurotoxic effects of oxadiazon, suggesting a potential role of this herbicide in the onset of neurodegenerative diseases."

Related Drugs and Biologics

1.	Protoporphyrinogen Oxidase (Protox)
2.	Herbicides
3.	butachlor (Machete)
4.	Peroxisome Proliferator-Activated Receptors (PPAR)
5.	Matrix Metalloproteinase 1 (Interstitial Collagenase)
6.	Porphyrins
7.	Pentachlorophenol (Sodium Pentachlorophenate)
8.	Hexachlorobenzene (HCB)
9.	Emulsions
10.	Chlorpyrifos (Lorsban)