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aflatoxicol (aflatoxin R)
metabolite of aflatoxin B; RN given refers to (1S-(1alpha,6beta,9abeta))-isomer; structure
Also Known As:
aflatoxin R
; aflatoxicol, (1R-(1alpha,6aalpha,9aalpha))-isomer
Networked:
13
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrans: 130
Benzopyrans: 195
Aflatoxins: 1770
aflatoxicol: 13
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzopyrans: 195
Aflatoxins: 1770
aflatoxicol: 13
Biological Factors: 2472
Biological Toxins: 20
Mycotoxins: 1745
Aflatoxins: 1770
aflatoxicol: 13
Related Diseases
1.
Kwashiorkor
01/01/1986 - "
The ratio of AFB1 to AFM1 was higher in the sera and urines of kwashiorkors than in controls, suggesting that the normal transformation of AFB1 to AFM1 may be impaired in kwashiorkor with consequent increase in transformation of AFB1 to aflatoxicol.
"
09/25/1982 - "
The presence of aflatoxicol in the sera of children with kwashiorkor but not in the others suggests a difference in metabolism between the two groups.
"
01/01/1986 - "
Aflatoxicol was detected in the sera of 16 (11.6%) kwashiorkor, in six (6.1%) marasmic kwashiorkor, but in none of the controls and only once in marasmus.
"
09/01/1986 - "
These results confirm previous findings of aflatoxin B1 and aflatoxicol in the livers of children with kwashiorkor and provide further evidence of associations between these toxic compounds and kwashiorkor which might have relevance to the aetiology and pathogenesis of this disease which as yet remain mysterious.
"
09/25/1982 - "
Aflatoxicol, a metabolite of aflatoxins B1 and B2, was detected in the sera of children with kwashiorkor and marasmic kwashiorkor but not in the controls and only once in a marasmic child.
"
2.
Protein-Energy Malnutrition (Marasmus)
01/01/1986 - "
Aflatoxicol was detected in the sera of 16 (11.6%) kwashiorkor, in six (6.1%) marasmic kwashiorkor, but in none of the controls and only once in marasmus.
"
03/01/1986 - "
Aflatoxins B1, B2 and aflatoxicol were detected in 5 of the 16 biopsies from kwashiorkor but in none of 11 biopsies from marasmus or marasmic kwashiorkor.
"
01/01/1984 - "
Aflatoxicol, a metabolite of aflatoxin B1 was detected in serum in kwashiorkor and marasmic kwashiorkor but not in normally nourished children and only once in marasmus.
"
3.
Carcinogenesis
04/21/1978 - "
The formation of aflatoxicol both in vitro and in vivo may be an indicatory of species sensitivity to aflatoxin-induced carcinogenesis and may be useful in the prediction of human susceptibility.
"
08/01/1994 - "
Quantitative carcinogenesis and dosimetry in rainbow trout for aflatoxin B1 and aflatoxicol, two aflatoxins that form the same DNA adduct.
"
4.
Jaundice (Icterus)
01/01/1995 - "
First, cord blood samples from 37 neonates who subsequently developed jaundice and from 40 non-jaundiced (control) babies were analysed for six major aflatoxins and aflatoxicol.
"
5.
Hepatocellular Carcinoma (Hepatoma)
03/01/1981 - "
Aflatoxicol-induced hepatocellular carcinoma in rainbow trout (Salmo gairdneri) and the synergistic effects of cyclopropenoid fatty acids.
"
Related Drugs and Biologics
1.
Aflatoxins
2.
Aflatoxin B1 (Aflatoxin B)
3.
DNA Adducts
4.
Aflatoxin M1 (Aflatoxin M)
5.
Fatty Acids (Saturated Fatty Acids)
6.
Acids
7.
sulfuric acid