viridin

bacteriocins of alpha-hemolytic streptococcal isolates; RN given refers to (1S-(1alpha,2alpha,11balpha))-isomer

Also Known As:

viridin A; viridin B; viridin C; (1S-(1 alpha,2 alpha,11b alpha))-1,7,8,11b-tetrahydro-1-hydroxy-2-methoxy-11b-methylcyclo penta(7,8)phenanthro(10,1-bc)furan-3,6,9(2H)-trione

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Androstanes: 11
      - Androstenes: 5
        viridin: 2
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Bacteriocins: 556
        viridin: 2
  - Bacterial Proteins: 394
    - Bacteriocins: 556
      - viridin: 2

Experts

1.	Blois, Joseph: 2 articles (08/2009 - 12/2008)
2.	Cortez-Retamozo, Virna: 2 articles (08/2009 - 12/2008)
3.	Josephson, Lee: 2 articles (08/2009 - 12/2008)
4.	Weissleder, Ralph: 2 articles (08/2009 - 12/2008)
5.	Yuan, Hushan: 2 articles (08/2009 - 12/2008)
6.	Benoist, Christophe: 1 article (08/2009)
7.	Ellson, Chris: 1 article (08/2009)
8.	Mahmood, Umar: 1 article (08/2009)
9.	Mathis, Diane: 1 article (08/2009)
10.	Ortiz-Lopez, Adriana: 1 article (08/2009)

Related Diseases

1.	Inflammation (Inflammations) 12/01/2008 - "Using these real-time imaging methods, we confirmed the immunosuppressive effects of the glucocorticoid drug dexamethasone in the mouse model of allergic airway inflammation and identified a viridin-derived prodrug that potently inhibited the accumulation and enzyme activity of eosinophils in the lungs. "
2.	Arthritis (Polyarthritis) 08/01/2009 - "Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function." 08/01/2009 - "To test a novel self-activating viridin (SAV) prodrug that slowly releases wortmannin, a potent phosphoinositide 3-kinase inhibitor, in a model of antibody-mediated inflammatory arthritis. "

Related Drugs and Biologics

1.	Prodrugs
2.	Phosphatidylinositols (Phosphatidylinositol)
3.	Glucocorticoids
4.	Enzymes
5.	Dexamethasone (Maxidex)
6.	Wortmannin