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terlipressin

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Also Known As:

Gly-Gly-Gly-8-Lys-vasopressin; N-(alpha)-glycyl-glycyl-glycyl-8-lysine vasopressin; Remestyp; TGLVP; glipressin; glycylpressin; glypressin; terlypressin; triglycyl lysine vasopressin; triglycyl-(8-lysine)vasopressin; triglycylvasopressin; vasopressin, tri-Gly-8-Lys-; N-(N- (N-glycylglycyl)glycyl)-8-L-lysinevasopressin

Networked: 482 relevant articles (81 outcomes, 117 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Westphal, Martin: 16 articles (06/2011 - 02/2003)
2.	Morelli, Andrea: 15 articles (12/2013 - 04/2004)
3.	Ertmer, Christian: 13 articles (06/2011 - 08/2006)
4.	Ginès, Pere: 9 articles (02/2015 - 10/2002)
5.	Krag, Aleksander: 9 articles (09/2013 - 12/2007)
6.	Bendtsen, Flemming: 9 articles (05/2013 - 05/2005)
7.	Tsianos, Epameinondas V: 9 articles (08/2012 - 07/2005)
8.	López-Herce, Jesús: 8 articles (01/2015 - 01/2006)
9.	Møller, Søren: 8 articles (05/2013 - 05/2005)
10.	Lange, Matthias: 8 articles (05/2011 - 09/2007)

Related Diseases

1.	Hemorrhage 04/01/2012 - "In patients with esophageal variceal bleeding, a 24-h course of terlipressin is as effective as a 72-h course when used as an adjunctive therapy to successful EVBL." 04/01/2010 - "In patients with variceal bleeding, the bleeding control is significantly improved by early administration of terlipressin. " 09/01/1991 - "High-dose terlipressin (84%) seemed to be more effective in the initial control of bleeding than low-dose terlipressin (67%); however this difference was not significant. " 05/01/2005 - "Portal hypotensive effect of terlipressin is less effective when given during hemorrhage than in stable state. " 01/01/2003 - "On the basis of a 34% relative risk reduction in mortality, terlipressin should be considered to be effective in the treatment of acute variceal hemorrhage. "
2.	Hepatorenal Syndrome 05/01/2011 - "Finally, we understand its use associated to terlipressin seems to be the best treatment strategy for type I hepatorenal syndrome. " 10/01/2008 - "Studies suggest that terlipressin is effective in the treatment of hepatorenal syndrome (HRS). " 03/01/2012 - "Treatment with terlipressin and albumin has been reported recently to be effective in improving renal function in the treatment of cirrhotic patients with hepatorenal syndrome (HRS). " 01/01/2010 - "Terlipressin plus albumin is an effective treatment for type 1 hepatorenal syndrome (HRS), but approximately only half of the patients respond to this therapy. " 11/01/2009 - "Terlipressin has been shown to be effective in the management of hepatorenal syndrome. "
3.	Hypotension (Low Blood Pressure) 11/01/2011 - "Although the number of reported infants is little, terlipressin appears to be an effective rescue treatment in different scenarios of refractory neonatal hypotension. " 04/01/2008 - "Terlipressin promptly reversed hypotension and improved tissue perfusion without adverse effects. " 11/01/2011 - "The aim of this study is to describe original clinical scenarios in which terlipressin, in newborns and infants, resolved the catecholamine-refractory hypotension. " 01/01/2010 - "The objective of this study was to report the effects of Terlipressin treatment in 2 potential organ donors with intractable, catecholamine-resistant hypotension. " 01/01/2013 - "terlipressin) in decreasing mortality and adverse neurodevelopmental outcomes, and improving survival in neonates with refractory hypotension. "
4.	Fibrosis (Cirrhosis) 08/01/2002 - "In patients with type 1 HRS treated with terlipressin, patients with improved renal function had less severe cirrhosis (Child-Pugh >10 but < or =13) than patients without. " 01/01/2010 - "The aim of this study was to assess predictive factors of response to treatment with terlipressin and albumin in patients with type 1 HRS. Thirty-nine patients with cirrhosis and type 1 HRS were treated prospectively with terlipressin and albumin. " 11/01/2009 - "The aim of the present study was to assess the effects of terlipressin on systemic, hepatic and renal hemodynamics in cirrhosis. " 05/01/2008 - "The aim of this study was to evaluate the efficacy and safety of terlipressin, a systemic arterial vasoconstrictor, for cirrhosis type 1 HRS. A prospective, randomized, double-blind, placebo-controlled clinical trial of terlipressin was performed. " 01/01/2006 - "Therefore, the aim of the present study was to investigate the preventive effect of terlipressin on paracentesis-induced circulatory dysfunction in patients with cirrhosis after therapeutic paracentesis and compared with that of intravenous albumin. "
5.	Septic Shock (Toxic Shock Syndrome) 06/01/2011 - "In fluid-resuscitated patients with septic shock (with a MAP between 65 and 75 mmHg), a bolus infusion of 0.5 mg terlipressin was effective in reducing NE requirements without worsening microcirculatory blood flow. " 10/01/2006 - "Our data suggest that terlipressin is effective in septic shock. " 06/01/2011 - "The objective of the present study was, therefore, to elucidate the effects of a single terlipressin bolus dose of 0.5 mg on microcirculatory perfusion in patients with catecholamine-dependent septic shock. " 01/01/2009 - "Use of terlipressin in septic shock relies on a series of European studies resulting in a better knowledge of this vasopressive agent. " 06/01/2008 - "Future studies are required before any recommendations on the use of terlipressin in children with septic shock can be made."

Related Drugs and Biologics

1.	Vasopressins (Vasopressin)
2.	Somatostatin (Somatotropin Release-Inhibiting Factor)
3.	Octreotide (Sandostatin)
4.	Nitroglycerin (Dynamite)
5.	Vasoconstrictor Agents
6.	Norepinephrine (Noradrenaline)
7.	Arginine Vasopressin (Argipressin)
8.	Nitric Oxide (Nitrogen Monoxide)
9.	Midodrine (Midon)
10.	Ornipressin

Related Therapies and Procedures

1.	Sclerotherapy
2.	Liver Transplantation
3.	Balloon Occlusion
4.	Transplants (Transplant)
5.	Anesthesia