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bipiperidyl mustard
RN given refers to parent cpd; structure
Also Known As:
bipiperidyl mustard dihydrochloride; 1,1'-bis(beta-chloroethyl)-4,4'-bipiperidine
Networked:
9
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Halogenated Hydrocarbons: 42
Mustard Compounds: 3
bipiperidyl mustard: 9
Related Diseases
1.
Obesity
05/28/1986 - "
Bipiperidyl mustard (BPM) primarily destroys VMH neurons, but has produced only a slight obesity even when rats were maintained on high-fat diets.
"
02/01/1983 - "
Administration of goldthioglucose (GTG) or bipiperidyl mustard (BPM) causes obesity and lesions in hypothalamus, medulla, and other regions of the brain.
"
09/28/1981 - "
Bipiperidyl mustard produces brain lesions and obesity in the rat.
"
11/01/1980 - "
The induction of obesity in the rat with bipiperidyl mustard.
"
12/01/1967 - "
Metabolic investigations during the development of obesity in bipiperidyl mustard-treated mice.
"
2.
Hyperphagia (Overeating)
01/01/1985 - "
A single systemic injection of bipiperidyl mustard (BPM) in the adult rat produces brain lesions and associated obesity without hyperphagia.
"
11/01/1980 - "
1. Bipiperidyl mustard produced increased adiposity in the rat without excessive weight gain or hyperphagia.
"
05/28/1986 - "
Components of hypothalamic obesity: bipiperidyl-mustard lesions add hyperphagia to monosodium glutamate-induced hyperinsulinemia.
"
3.
Weight Gain
11/01/1980 - "
1. Bipiperidyl mustard produced increased adiposity in the rat without excessive weight gain or hyperphagia.
"
4.
Hyperinsulinism (Hyperinsulinemia)
05/28/1986 - "
Components of hypothalamic obesity: bipiperidyl-mustard lesions add hyperphagia to monosodium glutamate-induced hyperinsulinemia.
"
5.
Body Weight (Weight, Body)
01/01/1984 - "
Bi-weekly body weights, and eight week live, carcass, and abdominal fat plus carcass weights were depressed in chicks injected with bipiperidyl mustard, the depression being significant for eight-week abdominal fat weights.
"
01/01/1984 - "
Following a 48 h fasting period after hatching, male Cobb broiler chicks were injected with either bipiperidyl mustard (intraperitoneally; 0.01 and 0.02 mg/g body weight) or goldthioglucose (intracardially; 0.25 mg/g body weight).
"
Related Drugs and Biologics
1.
Glutamic Acid (Glutamate)
2.
Insulin (Novolin)
3.
Sodium Glutamate (Accent)
4.
Aurothioglucose (Gold 50)