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adrenosterone

Also Known As:

11-ketoandrostenedione; 4-androstene-3,11,17-trione; adrenosterone, 3H-labeled; androst-4-ene-3,11,17-trione

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Androstanes: 11
      - Androstenes: 5
        adrenosterone: 9

Experts

1.	Quanson, Jonathan L: 2 articles (01/2017 - 11/2013)
2.	Storbeck, Karl-Heinz: 2 articles (01/2017 - 11/2013)
3.	Basheer, Faiza: 1 article (01/2021)
4.	Gibert, Yann: 1 article (01/2021)
5.	Monroe, Jerry D: 1 article (01/2021)
6.	Dong, Shikun: 1 article (01/2020)
7.	Dong, Weida: 1 article (01/2020)
8.	Gong, Zhiyuan: 1 article (01/2020)
9.	Liu, Jinhui: 1 article (01/2020)
10.	Lu, Jeng-Wei: 1 article (01/2020)

Related Diseases

1.	Neoplasm Metastasis (Metastasis) 01/01/2020 - "A Novel Zebrafish Model of Metastasis Identifies the HSD11β1 Inhibitor Adrenosterone as a Suppressor of Epithelial-Mesenchymal Transition and Metastatic Dissemination." 10/05/2022 - "Furthermore, 11β-hydroxysteroid dehydrogenase 1 (HSD11β1) and serotonin receptor 2C (HTR2C), the primary targets of adrenosterone and pizotifen, respectively, promoted metastasis through induction of epithelial-mesenchymal transition (EMT). " 01/01/2021 - "Xmrk models of melanoma have shown that inhibitors of PI3K and MEK have an anti-cancer effect, and in HCC, that the steroidal drug, adrenosterone, can prevent metastasis and recover E-cadherin expression, suggesting that fish Xmrk models can exploit similarities with EGFR signal transduction to identify and study new chemotherapeutic drugs."
2.	Neoplasms (Cancer) 01/01/2021 - "Xmrk models of melanoma have shown that inhibitors of PI3K and MEK have an anti-cancer effect, and in HCC, that the steroidal drug, adrenosterone, can prevent metastasis and recover E-cadherin expression, suggesting that fish Xmrk models can exploit similarities with EGFR signal transduction to identify and study new chemotherapeutic drugs."
3.	Melanoma (Melanoma, Malignant) 01/01/2021 - "Xmrk models of melanoma have shown that inhibitors of PI3K and MEK have an anti-cancer effect, and in HCC, that the steroidal drug, adrenosterone, can prevent metastasis and recover E-cadherin expression, suggesting that fish Xmrk models can exploit similarities with EGFR signal transduction to identify and study new chemotherapeutic drugs."
4.	Atherosclerotic Plaque (Atheroma) 01/07/1957 - "[Protective effect of adrenosterone in experimental adrenalin-induced atheroma]."
5.	Adrenocortical Carcinoma 05/16/2023 - "The reduction conversion of 11-hydroxyandrostenedione to 11-ketoandrostenedione and 11-ketoandrostenedione to 11-ketotestosterone were independently associated with adrenal cortical carcinoma. "

Related Drugs and Biologics

1.	Mitogen-Activated Protein Kinase Kinases (MEKs)
2.	Cadherins (E-Cadherin)
3.	Oxidoreductases (Dehydrogenase)
4.	Androgens
5.	11-ketotestosterone
6.	Hexamethonium (Hexamethonium Bromide)
7.	Serotonin Receptors
8.	Pizotyline (BC 105)
9.	Clofazimine (Lamprene)
10.	ikarugamycin