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talinolol

Also Known As:
1-(4-cyclohexylureidophenoxy)-2-hydroxy-3-tert-butylaminopropane; cordanum; talinolol acetate; talinolol benzoate; talinolol hydrochloride; talinolol monoacetate; talinolol monohydrochloride; talinolol mononitrate; talinolol monosalicylate; talinolol nitrate; talinolol oxalate; talinolol oxalate (2:1); talinolol salicylate; talinolol sulfate; talinolol sulfate (2:1); talinolol tartrate (2:1), L-(+)-isomer; talinolol tartrate, L-(+)-isomer; talinolol, (+-)-isomer; (+-)-N-cyclohexyl-N'-(4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)phenyl)urea
Networked: 45 relevant articles (1 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Siegmund, Werner: 3 articles (01/2019 - 02/2002)
2. Terhaag, B: 3 articles (02/2005 - 07/2000)
3. Cascorbi, Ingolf: 2 articles (01/2019 - 09/2004)
4. Wegner, Danilo: 2 articles (01/2019 - 09/2004)
5. Kroemer, Heyo K: 2 articles (09/2004 - 02/2002)
6. Zschiesche, Michael: 2 articles (09/2004 - 02/2002)
7. Oertel, R: 2 articles (02/2001 - 07/2000)
8. Bruckmueller, Henrike: 1 article (01/2019)
9. Brueck, Susanne: 1 article (01/2019)
10. Busch, Diana: 1 article (01/2019)

Related Diseases

1. Stable Angina
2. Hypertension (High Blood Pressure)
3. Body Weight (Weight, Body)
03/01/2016 - "The AUC and other PK data of talinolol, corrected for body weight, did not differ between genders after oral administration. "
02/01/2002 - "Because talinolol is marketed as a racemate, we reevaluated the serum-concentration time profiles of talinolol of a previously published study with single intravenous (30 mg) and repeated oral talinolol (100 mg for 14 days) before and after comedication of rifampicin (600 mg per day for 9 days) in eight male healthy volunteers (age 22-26 years, body weight 67-84 kg) with respect to differences in the kinetic profiles of the two enantiomers S(-) talinolol and R(+) talinolol. "
07/01/2000 - "Pharmacokinetics of digoxin (0.5 mg orally), talinolol (30 mg intravenously and 100 mg orally), and digoxin plus talinolol orally, as well as digoxin plus talinolol intravenously, were assessed in five male and five female healthy volunteers (age range, 23 to 30 years; body weight, 60 to 95 kg) in a changeover study with at least a 7-day washout period. "
08/15/1982 - "It is reported on a severe talinolol intoxication of a 19-year-old female patient who on suicidal purpose had taken 1.25-1.5 g talinolol (cordanum) (= 25-30 mg/kg body weight). "
09/01/2004 - "To evaluate whether it also regulates the multidrug transporter proteins P-glycoprotein (P-gp) and multidrug resistance protein MRP2 in humans, duodenal expression of multidrug resistance gene MDR1 messenger ribonucleic acid (mRNA) and MRP2 mRNA, content of P-gp and MRP2, and disposition of the nonmetabolized P-gp substrate talinolol after intravenous (30 mg) and long-term oral administration (100 mg for 19 days) were assessed in 7 healthy subjects (age, 23-35 years; body weight, 64-93 kg) before and after comedication of carbamazepine (600 mg for 14-18 days). "
4. Angina Pectoris
5. Malnutrition (Nutritional Deficiencies)

Related Drugs and Biologics

1. Propranolol (Inderal)
2. Atenolol (Tenormin)
3. Nifedipine (Adalat)
4. Proteins (Proteins, Gene)
5. hydrochlorothiazide-triamterene (Dyazide)
6. Rifampin (Rifampicin)
7. Saquinavir (Invirase)
8. Metaproterenol (Alupent)
9. Metoprolol (Toprol-XL)
10. Digoxin (Digitek)

Related Therapies and Procedures

1. Therapeutics
2. Oral Administration
3. Intravenous Administration
4. Intravenous Injections
5. Aftercare (After-Treatment)