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nardosinone

sesquiterpene peroxide; structure

Also Known As:

1,3a,4,7,8,9,9a,9b-octahydro-1,1,9,9a-tetramethyl- 5H-naphtho(2,1c)(1,2)dioxol-5-one

Networked: 12 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - Polycyclic Sesquiterpenes: 9
        nardosinone: 12
Polycyclic Compounds: 6
- Polycyclic Sesquiterpenes: 9
  - nardosinone: 12

Experts

1.	Shi, Jin-Li: 3 articles (09/2022 - 01/2014)
2.	Bian, Li-Hua: 2 articles (09/2022 - 01/2021)
3.	Guo, Jian-You: 2 articles (09/2022 - 01/2021)
4.	Li, Qiu-Yu: 2 articles (09/2022 - 01/2021)
5.	Yao, Zi-Wei: 2 articles (09/2022 - 01/2021)
6.	Li, Jia-Yuan: 1 article (09/2022)
7.	Wan, Guo-Hui: 1 article (09/2022)
8.	Wang, Xiao-Mei: 1 article (09/2022)
9.	Wang, Yu-Qing: 1 article (09/2022)
10.	Wang, Zhe-Yi: 1 article (09/2022)

Related Diseases

1.	Parkinson Disease (Parkinson's Disease) 09/01/2022 - "This further confirms that nardosinone can regulate the slc38a2 gene, a potential new target for the treatment of Parkinson's disease, and plays an anti-PD role through the GABAergic synaptic and cAMP pathways." 09/01/2022 - "In a rotenone-induced Parkinson's disease (PD) rat model, behavioral investigation, pathological examination, inflammatory factor analysis, and mitochondrial structure and function investigation verified the anti-PD efficacy of nardosinone. " 01/01/2021 - "Nardosinone Alleviates Parkinson's Disease Symptoms in Mice by Regulating Dopamine D2 Receptor."
2.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2014 - "In conclusion, this study reveals the regulatory effects of Nardosinone on neural stem cells, which may have significant implications for the treatment of brain injury and neurodegenerative diseases. " 10/05/2021 - "Overall, nardosinone has the potential to treat bacterial infections, periodontitis, cardiac diseases, neurodegenerative diseases and cancer. "
3.	Alveolar Bone Loss 01/01/2017 - "In this study, the effects of nardosinone (Nd) on bone were tested in a model of lipopolysaccharide (LPS)-induced alveolar bone loss, and the associated mechanisms were elucidated. "
4.	Osteoarthritis 01/01/2023 - "In the current study, the effects of nardosinone on osteoarthritis (OA) were first assessed and the mechanism underlying the effects was explored by detecting changes in the miR-218-5p/NUMB axis. " 01/01/2023 - "Nardosinone suppresses monoiodoacetate-induced osteoarthritis in rats: The key role of the miR-218-5p/NUMB axis."
5.	Brain Injuries (Brain Injury) 01/01/2014 - "In conclusion, this study reveals the regulatory effects of Nardosinone on neural stem cells, which may have significant implications for the treatment of brain injury and neurodegenerative diseases. "

Related Drugs and Biologics

1.	Rotenone
2.	Lipopolysaccharides
3.	ErbB Receptors (EGF Receptor)
4.	Cyclin-Dependent Kinase 2
5.	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
6.	Mitogen-Activated Protein Kinase Kinases (MEKs)
7.	Dopamine D2 Receptors (Dopamine D2 Receptor)
8.	Sesquiterpenes
9.	Antidepressive Agents (Antidepressants)
10.	Anti-Arrhythmia Agents