HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

methenamine hippurate (Hiprex)

Subscribe to New Research on methenamine hippurate

both parts of molecule contribute to its antibacterial action

Also Known As:

Hiprex; Urex; 3M brand 1 of methenamine hippurate; 3M brand 2 of methenamine hippurate; Aventis Behring brand of methenamine hippurate; Hip-Rex; Klinge brand of methenamine hippurate; United Drug brand of methenamine hippurate; Urotractan; hexamine hippurate; hexamethylene tetramine hippurate

Networked: 46 relevant articles (2 outcomes, 10 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Simpson, J M: 2 articles (08/2007 - 01/2007)
2.	Lee, B B: 2 articles (08/2007 - 01/2007)
3.	Bhuta, T: 2 articles (01/2007 - 01/2002)
4.	Schiøtz, Hjalmar A: 2 articles (01/2006 - 08/2002)
5.	Simpson, Judy M: 1 article (01/2012)
6.	Bhuta, Tushar: 1 article (01/2012)
7.	Craig, Jonathan C: 1 article (01/2012)
8.	Lee, Bon San B: 1 article (01/2012)
9.	Sandvik, Arne K: 1 article (09/2010)
10.	Aarsand, Aasne K: 1 article (09/2010)

Related Diseases

1.	Urinary Tract Infections (Urinary Tract Infection) 01/01/2012 - "Methenamine hippurate for preventing urinary tract infections." 01/01/2007 - "Methenamine hippurate for preventing urinary tract infections." 01/01/2006 - "Methenamine hippurate prophylaxis effectively reduces postoperative urinary tract infection." 01/01/2002 - "Methenamine hippurate for preventing urinary tract infections." 12/01/1994 - "She had been taking methenamine hippurate for several years to prevent urinary tract infections after an cystopexia operation. "
2.	Bacteriuria 08/01/1968 - "Persistence of bacteriuria following gynaecological surgery: a trial of methenamine hippurate." 01/01/2012 - "Subgroup analyses suggested that methenamine hippurate may have some benefit in patients without renal tract abnormalities (symptomatic UTI: RR 0.24, 95% CI 0.07 to 0.89; bacteriuria: RR 0.56, 95% CI 0.37 to 0.83), but not in patients with known renal tract abnormalities (symptomatic UTI: RR 1.54, 95% CI 0.38 to 6.20; bacteriuria: RR 1.29, 95% CI 0.54 to 3.07). " 01/01/2007 - "Subgroup analyses suggested that methenamine hippurate may have some benefit in patients without renal tract abnormalities (symptomatic UTI: RR 0.24, 95% CI 0.07 to 0.89; bacteriuria: RR 0.56, 95% CI 0.37 to 0.83), but not in patients with known renal tract abnormalities (symptomatic UTI: RR 1.54, 95% CI 0.38 to 6.20; bacteriuria: RR 1.29, 95% CI 0.54 to 3.07). " 01/01/2002 - "An exploration of heterogeneity raises the (hypothesis generating) possibility that methenamine hippurate may have some efficacy in patients without but not in patients with known upper renal tract abnormality (with asymptomatic bacteriuria as the outcome measure). " 11/01/1980 - "Catheterized patients with heavy bacteriuria and short catheter life received a short-course of antimicrobial therapy and then were allocated at random to double-blind treatment for 5 months with methenamine hippurate (MH), 1 g three times daily, or placebo 1 g 3 times daily. "
3.	Sepsis (Septicemia) 01/01/1980 - "In the second group, 7 patients developed postoperative sepsis with systemic symptoms while on therapy with methenamine hippurate: therapy was then changed to cephazolin--cephalexin and the patients were cured. "
4.	Infection 05/07/1984 - "[The preventive effect of methenamine hippurate (Haiprex) on urinary infections after short-term catheterization. " 01/01/1976 - "During the six month period with "Hiprex' there were far fewer re-infections than in the previous six months during which time they had received intermittent antibiotic therapy and other long-term treatment. " 07/01/1966 - "[Hexamethylene-tetramine hippurate in the treatment of urinary infections]." 01/01/1979 - "The effect of short-term high-dose treatment with methenamine hippurate of urinary infection in geriatric patients with indwelling catheters. " 07/01/1981 - "Prevention of recurrent urinary infections in women: a comparative trial between nitrofurantoin and methenamine hippurate."
5.	Spinal Cord Injuries (Spinal Cord Injury) 08/01/2007 - "To determine whether Methenamine Hippurate (MH) or cranberry tablets prevent urinary tract infections (UTI) in people with neuropathic bladder following spinal cord injury (SCI). " 09/01/1985 - "We conducted 202 trials in 161 male hospital patients to determine if prophylactic administration of ascorbic acid or antibacterials (trimethoprim-sulfamethoxazole, nalidixic acid, methenamine hippurate or nitrofurantoin macrocrystals) would prevent bacteriuria infections in spinal cord injury patients who had had at least 1 bout of bacteriuria. "

Related Drugs and Biologics

1.	Cephalexin (Cefalexin)
2.	Cefazolin (Ancef)
3.	methenamine hippurate (Hiprex)
4.	Nitrofurantoin (Macrodantin)
5.	Trimethoprim (Proloprim)
6.	Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)
7.	Anti-Bacterial Agents (Antibiotics)
8.	Ascorbic Acid (Vitamin C)
9.	Povidone-Iodine (Betadine)
10.	Nalidixic Acid

Related Therapies and Procedures

1.	Catheters
2.	Indwelling Catheters (Arterial Line)
3.	Drug Therapy (Chemotherapy)