elaidic acid

stereoisomer of oleic acid; RN given refers to parent cpd (E)-isomer; structure

Also Known As:

elaidate; elaidic acid, 1-(14)C-labeled, (E)-isomer; elaidic acid, 10-(14)C-labeled, (E)-isomer; elaidic acid, 14C-labeled, (E)-isomer; elaidic acid, 9-(14)C-labeled; elaidic acid, potassium salt, (E)-isomer; elaidic acid, sodium salt, (E)-isomer; trans-9-octadecenoic acid

Networked: 78 relevant articles (0 outcomes, 13 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Monounsaturated Fatty Acids: 676
      - Oleic Acids: 67
        elaidic acid: 78

Experts

1.	Fujii, Kiyomu: 5 articles (04/2018 - 01/2017)
2.	Kuniyasu, Hiroki: 5 articles (04/2018 - 01/2017)
3.	Ohmori, Hitoshi: 5 articles (04/2018 - 01/2017)
4.	Gunter, Marc J: 4 articles (04/2021 - 01/2015)
5.	Huybrechts, Inge: 4 articles (04/2021 - 01/2015)
6.	Masala, Giovanna: 4 articles (04/2021 - 01/2015)
7.	Skeie, Guri: 4 articles (04/2021 - 11/2011)
8.	Tjønneland, Anne: 4 articles (04/2021 - 11/2011)
9.	Weiderpass, Elisabete: 4 articles (04/2021 - 01/2015)
10.	Ardanaz, Eva: 4 articles (01/2021 - 11/2011)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1981 - "These data indicate that tumor cells handle elaidic acid differently than normal cells in some aspects of its metabolism." 12/01/1978 - "Tumor development was accompanied by an increase in elaidic acid of the host's liver. " 12/01/1978 - "On the other hand, elaidic acid incorporation into tumor cells was close to that of ascites fluid. " 11/01/2011 - "The main objective is to assess associations between processed food intakes and plasma phospholipid elaidic acid concentrations within the European Prospective Investigation into Cancer and Nutrition study. " 01/01/1981 - "These studies indicate that tumor cells take up elaidic acid at the same rate as stearic acids. "
2.	Colorectal Neoplasms (Colorectal Cancer) 04/01/2018 - "The present study examined the effects and signaling of elaidic acid (EA), a TFA, in colorectal cancer (CRC) cells. " 01/01/2017 - "In the present study, we examined the effects and signaling of elaidic acid (EA), a TFA, in colorectal cancer (CRC) cells. " 01/01/2017 - "This study examined the effects of elaidic acid (EA), a TFA, on colorectal cancer (CRC) progression. " 01/01/2017 - "Elaidic Acid, a Trans-Fatty Acid, Enhances the Metastasis of Colorectal Cancer Cells." 03/01/2016 - "PPL PA, elaidic acid, and SCD-1 and ELOVL-6 EAEs are associated with adenomas even after adjusting for obesity-related risk factors and may function as novel biomarkers of early colorectal cancer risk."
3.	Inflammation (Inflammations) 01/01/2022 - "Therefore, this paper focused on TFA, represented by elaidic acid (EA), to investigate the mechanism of liver inflammation. " 01/01/2020 - "Here, we show a novel microglial signaling pathway that induces inflammation and cell death, which is dramatically enhanced by elaidic acid (EA), the most abundant TFA derived from food. " 01/01/2020 - "Protective Effect of Se-Methylselenocysteine on Elaidic Acid-Induced Inflammation in Human Arterial Endothelial Cells." 01/01/2017 - "In RAW264.7 macrophages, the saturated FA, palmitate, markedly increased markers of inflammation and the unfolded protein response, whereas the trans-unsaturated elaidate and the cis-unsaturated oleate had the opposite effect. " 01/01/2020 - "Furthermore, we analyze the effects of elaidate administration on intestinal inflammation using 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis model in mice. "
4.	Cardiovascular Diseases (Cardiovascular Disease) 08/01/2010 - "These findings provide further support on the detrimental effects of elaidic acid in promotion and induction of cardiovascular diseases (CVD)." 01/01/2013 - "The aim of the study was to elucidate the hepatic response to the most abundant trans fatty acid in the human diet, elaidic acid, to help explain clinical findings on the relationship between trans fatty acids and cardiovascular disease. " 07/01/2010 - "Vaccenic acid (trans-11-C(18:1)) chemically resembles elaidic acid (trans-9-C(18:1)) which is assumed to increase the risk of cardiovascular diseases, and thus could exert similar effects. " 01/01/2016 - "Dietary fatty acids also include transform of unsaturated fatty acids and intake of transform of oleate (elaidate) is associated with cardiovascular disease. "
5.	Ehrlich Tumor Carcinoma 12/01/1978 - "The incorporation of elaidic acid into Ehrlich ascites tumor cells (EATC) upon feeding the host an elaidic acid-rich diet has been investigated in the present study. " 01/01/1981 - "Uptake and oxidation of elaidic acid by Ehrlich ascites tumor cells." 12/01/1978 - "The effect of elaidic acid incorporation upon the lipid composition of Ehrlich Ascites tumor cells and of the host's liver." 07/01/1981 - "Feeding elaidic acid (18:1 delta 9, trans) to Ehrlich ascites tumor-bearing animals resulted in tumors that incorporated more thymidine into their cells and into their acid-insoluble fraction as compared with those grown in animals fed the natural oleic acid (18:1 delta 3, cis)-rich diet. "

Related Drugs and Biologics

1.	Fatty Acids (Saturated Fatty Acids)
2.	Trans Fatty Acids
3.	Phospholipids (Phosphatides)
4.	11-octadecenoic acid (vaccenic acid)
5.	Linoleic Acid (Linoleate)
6.	Gemcitabine
7.	Esters
8.	Insulin (Novolin)
9.	CP 4126
10.	5'-oleoyl cytarabine

Related Therapies and Procedures

1.	Fat-Restricted Diet (Diet, Fat Restricted)
2.	Therapeutics
3.	Drug Therapy (Chemotherapy)