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buturon
Also Known As:
N'-(4-chlorophenyl)-N-methyl-N-(1-methyl-2-propynyl)urea
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Urea: 15015
Methylurea Compounds
buturon: 1
Related Diseases
1.
Neural Tube Defects (Exencephaly)
11/21/1977 - "
High doses of both substances given from day 6--15 of pregnancy produced minor numbers of wavy and fused ribs as well as hypoplasia of the upper jaw after application of monolinuron and exenteria and exencephaly after buturon.
"
2.
Cleft Palate (Palate, Cleft)
11/21/1977 - "
Administration of monolinuron between days 10 and 13 of gestation resulted a minor and that of buturon a clear increase of the number of cleft palates.
"
11/21/1977 - "
Pregnant female mice of the NMRI strain were administered orally 25--1000 mg monolinuron/kg (I) and 100-400 mg buturon/kg (II) on days 6--15 of gestation and, during defined phases of fetal development (days 10--13 after conception), 500 mg I/kg and 350 mg II/kg. Following administration of 10 doses, an increase of postimplantative losses and clear retardation of development in the upper dose range from 100 mg I/kg and 300 mg II/kg as well as a dose-dependent increase of the rate of cleft palates could be observed.
"
Related Drugs and Biologics
1.
monolinuron