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5-vinyl-2'-deoxyuridine

structure

Also Known As:

2'-deoxy-5-vinyluridine; 2'-deoxy-5-ethenyluridine

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Uridine: 1186
        Deoxyuridine: 331
        5-vinyl-2'-deoxyuridine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Uridine: 1186
      - Deoxyuridine: 331
        5-vinyl-2'-deoxyuridine: 2
  - Deoxyribonucleosides: 34
    - Deoxyuridine: 331
      - 5-vinyl-2'-deoxyuridine: 2

Related Diseases

1.

Neoplasms (Cancer)

10/01/2023 - "For cancer treatment, nucleoside analogues (NA) such as 5-vinyl-2'-deoxyuridine (VdU) can be metabolically incorporated into cancer cell DNA and subsequently "clicked" to form a toxic product. "
10/01/2023 - "DNA templated Click Chemistry via 5-vinyl-2'-deoxyuridine and an acridine-tetrazine conjugate induces DNA damage and apoptosis in cancer cells."
01/01/1980 - "The chemical syntheses of some 5-substituted uracil deorivatives, in particular 5-vinyl-2'-deoxyuridine, 5-ethynyl-2'-deoxyuridine and 4-(2-bromovinyl)-2'-deoxy-uridine are reviewed and their potential as radiation sensitizing agents, anti-cancer agents and antiviral agents is discussed. "

Related Drugs and Biologics

1.	Uracil
2.	Radiation-Sensitizing Agents
3.	Nucleosides
4.	DNA (Deoxyribonucleic Acid)
5.	Antiviral Agents (Antivirals)
6.	Acridines
7.	5-ethynyl-2'-deoxyuridine