oxibendazole

06/01/1979 - "The efficacy of oxibendazole given at dose level of 10 mg/kg of body weight was determined by 10 critical tests in foals and by 2 clinical trials in 20 foals (16 treated, 4 nontreated), with special interest in the drug activity against Parascaris equorum. "
10/01/1976 - "In the first study, artificially infected calves were cleared of virtually all histotrophic larvae and adult parasites after medication with oxibendazole drench at a dose level of 10 mg/kg of body weight. "
04/01/1998 - "A single dose of 15 mg oxibendazole/kg body weight given to 70 dogs and to 29 cats reduced faecal worm egg counts (EPG) by 97.6% for Toxocara canis, 95.7% for Trichuris vulpis, 94.6% for Ancylostoma caninum, and 100% for Toxascaris leonina. "
12/01/1985 - "Oxibendazole (OBZ; 10 mg/kg of body weight) was administered to ponies at 8-week intervals to control strongylosis in a breeding band of Shetland-type ponies (n = 29 to 50) from October 1978 through September 1984. "
06/01/1977 - "Acute toxicity of oxibendazole was assessed with single oral doses given to mice (4 to 32 g/kg of body weight), sheep (230 to 600 mg/kg), and cattle (600 mg/kg); there were no ill effects. "

10/01/1976 - "Premix given on day 42 after infection removed 83 to 100% of adult O ostertagi, Nematodirus spp, C oncophora, O radiatum, and Trichuris spp. In a 3rd study, calves harboring a mixture of parasitic stages from artificial and pasture-acquired infections were medicated with oxibendazole at a dose of 15 mg/kg in premix form. "
10/01/1976 - "Oxibendazole at a dose level of 15 mg/kg in premix form was given to artificially infected calves 3, 7, or 42 days after infection in a 2nd study. "
03/01/1981 - "Clinical trials with fenbendazole and oxibendazole for Strongyloides westeri infection in foals."
06/01/1991 - "Compared with the value for control (nontreated) foals, treatment with ivermectin, pyrantel, and oxibendazole was 98.2, 74.2, and 44.5% effective, respectively, when administered 28 days after experimentally induced infection with P equorum. "
11/01/1989 - "The effect of three albendazole treatments at 5-week intervals, beginning at turnout in April, on cyathostome infections in Shetland ponies was compared with the effect of sequential treatments with albendazole, oxfendazole and oxibendazole. "

02/01/2018 - "Oxibendazole (OBZ) is an anthelmintic drug that has also shown promise in the treatment of malignancies. "
06/01/2019 - "The well-known and effective anthelmintic oxibendazole was recently shown to have a broad spectrum of biological abilities, such as anti-cancer and anti-inflammation activities. "
08/01/2020 - "The present review summarizes central literature regarding the anticancer effects of benzimidazole anthelmintics, including albendazole, parbendazole, fenbendazole, mebendazole, oxibendazole, oxfendazole, ricobendazole, and flubendazole in cancer cell lines, animal tumor models, and clinical trials. "

01/01/1990 - "[Clinical observations on the treatment of hookworm, Ascaris and Trichuris infection with oxibendazole]."
01/01/1990 - "340 cases of hookworm infection, 196 cases of ascariasis and 178 cases of trichuriasis were treated with an anthelmintic, oxibendazole, 15mg/kg.d x 3d; 102, 70 and 66 cases of respective infections were treated with pyrantel 10mg/kg.d x 3d and 108, 74 and 63 cases took placebo for comparison and as control under double-blind observations. "

02/01/2018 - "Oxibendazole inhibits prostate cancer cell growth."