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ibacitabine

antiherpetic agent

Also Known As:

2'-deoxy-5-iodocytidine; 5-iodo-2'-deoxycytidine; 5-iodo-2'-deoxycytidine, 125I-labeled; 5-iododeoxycytidine; iododeoxycytidine

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Cytidine: 535
        Deoxycytidine: 307
        Bromodeoxycytidine: 1
        ibacitabine: 7
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Cytidine: 535
      - Deoxycytidine: 307
        Bromodeoxycytidine: 1
        ibacitabine: 7
  - Deoxyribonucleosides: 34
    - Deoxycytidine: 307
      - Bromodeoxycytidine: 1
        ibacitabine: 7

Experts

1.	Dieguez, Cristina: 1 article (01/2017)
2.	Greer, Sheldon: 1 article (01/2017)
3.	Han, Tieran: 1 article (01/2017)
4.	Levi, Joe: 1 article (01/2017)
5.	Marquez, Victor E: 1 article (01/2017)
6.	McLean, Nicola: 1 article (01/2017)
7.	Reis, Isildinha: 1 article (01/2017)
8.	Saer, Rafael: 1 article (01/2017)

Related Diseases

1.	Herpetic Keratitis 01/01/1979 - "Experiences with iododeoxycytidine in the treatment of ocular herpes simplex infections." 11/01/1984 - "[Superficial herpetic keratitis: comparative double-blind treatment with iododeoxycytidine and acyclovir]."
2.	Neoplasms (Cancer) 11/01/1982 - "Virus grown in cells from 4 of 5 tumor lines demonstrated greater fractions mutated to iododeoxycytidine resistance than did virus grown in 7 normal human skin cell lines. " 01/01/2017 - "Among patients with colon (19) and pancreatic tumors (40), 53 and 68 %, respectively, displayed T/N values >4 for CD suggesting chemotherapy with 5-FdC, 4-N-methylamino-5-FdC, 5-trifluoromethyldeoxycytidine and radiosensitization with 5- CldC, 4-N-methylamino-5-CldC, 5-iododeoxycytidine and 5-bromodeoxycytidine. "
3.	Infections 01/01/1979 - "Experiences with iododeoxycytidine in the treatment of ocular herpes simplex infections." 12/01/1973 - "It is suggested that this difference in substrate specificity between virus-induced and host-cell enzymes may allow selective chemotherapy of herpes simplex infections with 5-bromo- or 5-iododeoxycytidine."
4.	Hypersensitivity (Allergy) 07/01/1987 - "Cross-allergy between 5-iodo-2'-deoxycytidine and idoxuridine."
5.	Herpes Zoster 11/01/1976 - "5-Bromodeoxycytidine (BrdC) and 5-iododeoxycytidine, at a concentration of 100 mug/ml, effectively inhibit the replication of varicella-zoster (VZ) virus in tissue culture. "

Related Drugs and Biologics

1.	Idoxuridine (Stoxil)
2.	Enzymes
3.	Acyclovir (Aciclovir)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)