delta-hydroxylysylnorleucine

RN given refers to cpd without isomeric designation

Also Known As:

5-hydroxylysinonorleucine; 5-hydroxylysylnorleucine; HLNL; delta-hydroxy-Lys-Nle; delta-hydroxylysylnorleucine, (L)-(2S)-isomer; hydroxylysinonorleucine; N(6)-(5-amino-5-carboxypentyl)-5-hydroxylysine

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - delta-hydroxylysylnorleucine: 7

Experts

1.	Brinckmann, Jürgen: 2 articles (06/2015 - 07/2014)
2.	Herold, Susanne: 2 articles (06/2015 - 07/2014)
3.	Mayer, Konstantin: 2 articles (06/2015 - 07/2014)
4.	Mižíková, Ivana: 2 articles (06/2015 - 07/2014)
5.	Morty, Rory E: 2 articles (06/2015 - 07/2014)
6.	Seeger, Werner: 2 articles (06/2015 - 07/2014)
7.	Steenbock, Heiko: 2 articles (06/2015 - 07/2014)
8.	Vadász, István: 2 articles (06/2015 - 07/2014)
9.	Madurga, Alicia: 1 article (06/2015)
10.	Ruiz-Camp, Jordi: 1 article (06/2015)

Related Diseases

1.	Hyperoxia 06/01/2015 - "Treatment of hyperoxia-exposed newborn mice with the lysyl oxidase inhibitor β-aminopropionitrile partially restored normal collagen levels, normalized the dihydroxylysinonorleucine-to-hydroxylysinonorleucine ratio, partially normalized desmosine and isodesmosine cross-links in insoluble elastin, and partially restored elastin foci structure in the developing septa. "
2.	Interstitial Lung Diseases (Interstitial Lung Disease) 02/01/1990 - "Lung tissue from patients with interstitial lung disease (ILD), adult respiratory distress syndrome (ARDS), and control subjects with no obvious fibrotic lung disease was analyzed for its content of the collagen cross-links hydroxylysinonorleucine (HLNL), dihydroxylysinonorleucine (DHLNL), and hydroxypyridinium (OHP). "
3.	Wounds and Injuries (Trauma) 01/01/1991 - "Treatment with BAPN (333 mg/kg BW/day) reduced the strength of the wounds by 59%, the HLNL by 50% and the DHLNL 57%, whereas the deposition of hydroxyproline did not seem to be influenced by BAPN treatment. " 01/01/1991 - "The mechanical strength of skin wounds as well as the deposition of hydroxyproline and KB3H4 reducible hydroxylysinonorleucine (HLNL) and dihydroxylysinonorleucine (DHLNL) cross-links in subcutaneously implanted cellulose sponges have been investigated in rats treated with aminoguanidine (AG) or beta-aminopropionitrile (BAPN). "
4.	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 02/01/1990 - "Lung tissue from patients with interstitial lung disease (ILD), adult respiratory distress syndrome (ARDS), and control subjects with no obvious fibrotic lung disease was analyzed for its content of the collagen cross-links hydroxylysinonorleucine (HLNL), dihydroxylysinonorleucine (DHLNL), and hydroxypyridinium (OHP). "
5.	Lung Diseases (Lung Disease) 02/01/1990 - "These results are consistent with data from animal models of fibrotic lung disease, suggesting that increases in the DHLNL:HLNL ratio of lung collagen may serve as a marker of an acute fibrotic episode, whereas increased lung collagen OHP content serves as a marker of chronic lung fibrosis. " 02/01/1990 - "Lung tissue from patients with interstitial lung disease (ILD), adult respiratory distress syndrome (ARDS), and control subjects with no obvious fibrotic lung disease was analyzed for its content of the collagen cross-links hydroxylysinonorleucine (HLNL), dihydroxylysinonorleucine (DHLNL), and hydroxypyridinium (OHP). "

Related Drugs and Biologics

1.	Collagen
2.	delta-hydroxylysylnorleucine
3.	Desmosine
4.	Aminopropionitrile
5.	5,5'-dihydroxylysylnorleucine
6.	Rimantadine
7.	Protein-Lysine 6-Oxidase (Lysyl Oxidase)
8.	Isodesmosine
9.	Hydroxyproline (4 Hydroxyproline)
10.	Elastin