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glycolaldehyde

structure

Also Known As:

hydroxyacetaldehyde

Networked: 38 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aldehydes: 2153
  - Acetaldehyde: 1345
    - glycolaldehyde: 38

Experts

1.	Mori, Shuji: 6 articles (11/2021 - 09/2009)
2.	Nishibori, Masahiro: 6 articles (11/2021 - 09/2009)
3.	Wake, Hidenori: 5 articles (11/2021 - 09/2009)
4.	Nishinaka, Takashi: 4 articles (11/2021 - 12/2018)
5.	Takahashi, Hideo: 4 articles (11/2021 - 12/2018)
6.	Yoshino, Tadashi: 4 articles (11/2021 - 09/2009)
7.	Liu, Keyue: 3 articles (11/2021 - 09/2009)
8.	Yamazaki, Yui: 3 articles (11/2021 - 12/2018)
9.	Gu, Min Ji: 2 articles (05/2022 - 01/2022)
10.	Ha, Sang Keun: 2 articles (05/2022 - 01/2022)

Related Diseases

1.	Acidosis 11/01/2000 - "Results showed early resuscitation with modified bovine Hb is superior to lactated Ringer's solution group in improving hemodynamic and acidosis, but the effect of polymerized Hb with glycolaldehyde were similar to fresh whole blood in this rat model." 01/01/2012 - "The EG biotransformation undergoes, mainly to glycolaldehyde and acids: glycolic, glyoxylic and oxalic acid, such metabolites, which exhibit strong narcotic effect on the central nervous system, causing profound metabolic acidosis and lead to severe nephropathy. " 09/01/1986 - "Ethylene glycol is metabolised more rapidly than methanol, via alcohol dehydrogenase to glycolaldehyde which is rapidly metabolised to glycolate, the metabolite mainly responsible for the metabolic acidosis in ethylene glycol poisoning. "
2.	Renal Insufficiency (Renal Failure) 08/30/2007 - "These results indicate that COM, and not glyoxylate or glycolaldehyde, is the toxic metabolite responsible for the acute tubular necrosis and renal failure that is observed in EG-poisoned patients." 11/01/2009 - "ROLE OF METABOLITES: Although the "aldehyde" metabolites of EG, glycolaldehyde, and glyoxalate, have been suggested as the metabolites responsible, recent studies have shown definitively that the accumulation of calcium oxalate monohydrate (COM) crystals in kidney tissue produces renal tubular necrosis that leads to kidney failure. "
3.	Necrosis 08/30/2007 - "These results indicate that COM, and not glyoxylate or glycolaldehyde, is the toxic metabolite responsible for the acute tubular necrosis and renal failure that is observed in EG-poisoned patients." 11/01/2009 - "ROLE OF METABOLITES: Although the "aldehyde" metabolites of EG, glycolaldehyde, and glyoxalate, have been suggested as the metabolites responsible, recent studies have shown definitively that the accumulation of calcium oxalate monohydrate (COM) crystals in kidney tissue produces renal tubular necrosis that leads to kidney failure. "
4.	Dehydration (Water Stress) 11/03/2004 - "Studies performed on model systems using pyrolysis-GC-MS analysis and (13)C-labeled sugars and amino acids in addition to ascorbic acid have indicated that certain amino acids such as serine and cysteine can degrade and produce acetaldehyde and glycolaldehyde that can undergo aldol condensation to produce furan after cyclization and dehydration steps. " 06/15/2013 - "Also, products resulting from dehydration, oxidation, and cleavage of a carbon-carbon bond at the reducing end of the corresponding non-modified oligosaccharide were formed, probably promoting the release of formaldehyde, formic acid, glycolaldehyde, glyoxal, acetic acid, glycolic acid, glyceraldehyde, 2-hydroxypropanedialdehyde and lactic acid. "
5.	Atherosclerosis 03/01/2007 - "In this study, we characterize lipid accumulation in primary human monocyte-derived macrophages, which are cells of immediate relevance to human atherosclerosis, on exposure to low-density lipoprotein glycated using methylglyoxal or glycolaldehyde. "

Related Drugs and Biologics

1.	Ringer's Lactate
2.	Aldehydes
3.	Proteins (Proteins, Gene)
4.	Sugars
5.	Serine (L-Serine)
6.	Pyruvaldehyde (Methylglyoxal)
7.	LDL Lipoproteins (beta Lipoproteins)
8.	Lipids
9.	Laminin (Merosin)
10.	Cysteine (L-Cysteine)

Related Therapies and Procedures

1.	Resuscitation